Card Set Information
antibiotics, antifungal, antiviral and antiparasitic
antibiotics can broken into 2 spectrums
broad and narrow
which bacteria is more dangerous, gram negative or gram positive?
pts often get worse before they get better
hard outer wall of gram negatives release toxins when ruptured
allergies and antibiotics
allergic reactions are common
repeated exposure sensitizes bodies defense mechanisms
may cause mild rash or more severe reacations
Name the groups of antibiotics
Which antibiotic agent was the first one discovered?
mulitiple variations avaliable now... G variations and V
greater effectiveness with oral administration
side effects of using penicillins
abdominal cramping and diarrhea
monilia (candida) overgrowth may cause oral thrush as well as vaginal and perineal infection
must be injected IM
useful for respiratory infections
prophylaxis against group B strep
derivative of penicillin g
can be taken orally
prevents rheumatic fever
if you are allergic to penicillin which antibiotic are you likely to be allergic to as well?
developed from mold
interferes with bacteria cell wall formation
cross-sensitivity associated with penicillin (25% chance)
can cause GI upset and skin rash
as generations increase they become more effective against gram negative bacteria
which generation of cephalosporin is more effective against gram negative bacteria, first-generation or fourth-generation?
usually given orally
effective against repiratory and soft tissue infections
treats mycoplasma infections
treats lyme diseas and rocky mountain spotted fever
which antibiotic generic ends in "cycline"
Why should tetracycline agents not be given to pregnant women and children younger than 8?
Name the antibiotic given to a pt with a pencillin allergy
effective against gram postives
treats upper and lower respiratory infections
usually used for community-acquired pneumonia
generics end in -mycin
bacteria quickly develop resistance
effective against respiratory, GI and STDs
used after older antibiotics are ineffective
long half-life (beware renal and liver pts)
more effecitve as serum concentration increases
which generic antibiotic ends in -ofloxacin?
What is a major side effect of many antibiotics?
hearing loss (ototoxicity)
ususally happens with aminoglycosides
those antibiotics reserved for serious infections by gram negatives
synthetics that resemble a bacterial enzyme (PABA)
must have adequate fluid intake may form crystals in kidney
treats uti and haemophilus influenzae
interferes with digoxin and phenytoin
may petentiate warfarin and antidiabetic agents
antifungal adminstration techniques
swish and swallow
Common antifungal drugs
fungal infections can be life threatening for pts with....
impaired immune systems
why are viruses hard to kill?
they develop an intimate host relationship
hard to kill virus w/o harming the body
hepatitis a, b, c
The progression of AIDS and drug-treatment decisions are based on which 2 mechanisms?
CD4 cell count
antivirals usually end in which suffix?