The equivalent of a TATA box (prokaryote) in a eukaryotic cell?
the segment of DNA in which a transcription factor binds (repressor/initiator)
A group of genes or a segment of DNA that functions as a single transcription unit. It is comprised of an operator, a promoter, and one or more structural genes that are transcribed into one polycistronic mRNA.
DNA inbetween clusters of genes; they have no genes
genes found in a genome that appear to have come from another species via horizontal gene transfer
a molecular method that uses a nucleic acid sequence complementary to an mRNA so that the two bind and the mRNA is effectively neutralized.
bacterial artificial chromosome
cloning vector replicated in bacteria that can hold an insert of about 150,000 base pairs.
BACs were used extensively in public HGP
meshwork of prokaryotes living collectively and resistamt to many chemical agents
random movement of particles or molecules that is powered by kinetic energy of the solution
CAMP factors (not cAMP)
secreted proteins that bind to antibodies and can form pores in the eukaryotic cell membranes
a method that allows small amounts of compounds to be seperated for further analysis.
The heart of automated DNA sequencing
a four-coloured graph produced from nonradioactive dideoxy sequencing methods
Clusters of Orthologous Groups
evolutionary related sequences from several microbial genomes.
the percentage of a genome that contains protein or funtional RNA coding DNA
overlapping DNA segments that as a collection form a longer and gapless segment of DNA
external guide sequence
short RNA sequences that bind to mRNAs that resembles a tRNA precursor.
RNaseP recognizes this pre-tRNA and cleaves the mRNA, thus inactivating it
control of gene activity without altering the DNA sequence
ex. imprinting (affected by methyltransferases adding a methyl group to cytosine bases in DNA)
gene rich, non-compacted portion of the chromosome that is transcriptionally active
part of the RNA molecule spliced together to form mRNA
biochemical term to descrbe how the products of a circuit pathway can either enhance or repress the circuit
DNA has been sequenced at least 8x and there are no gaps
contains no more than 1 error / 10,000 base pairs
$$$$ and time consuming
the movement of DNA from one species to another without sexual tranmission; mechanism uncertain, perhaps viral
process through which mammalian paternal and maternal alleles can be treated differently, depending on which parent contributed them to the offspring
collective noun that refers to insertions or deletions of bases in DNA
refer to 2 or more versions of highly similar proteins.
a sequence of amino acids or nucleotides that performs a particular role and is often conserved in other species or molecules
a potion of cDNA or gene that begins with a start codon and ends with a stop codon
two genes within a species that evolved from one another