Micro Parasites Ectoparasites skin infections Lima
Parasites and Ectoparasites causing skin infections, Micro Exam 2
Vector for Leishmaniasis
Sandfly Phlebotomus and Lutozomya
Commonly found in US soldiers returning from Afghanistan
Infective form of Leishmaniasis for Man vs Fly?
Promastogote vs Amastigote
Describe the general invasion of Leishmania
Promastigote invades macrophages
Transforms into nonmotile amastigote
Multiplies within cells of reticuloendothelial system (lymph, spleen, liver, bone marrow)
Initial skin ulcer (oriental sore) that hears in a year but leaves depigmented scar is characteristic of what?
Simple Cutaneous Leishmaniasis
Immunity and Hypersensitivity type associated with Leishmaniasis
Cell-mediated, Type IV (PPD-like test, positive only if cell-mediated immune system is intact, as in simple cutaneous Leishmaniasis)
Nodular skin lesion that does not ulcerate; over time more lesions arise diffusely over body with a concentration near the nose.
Diffuse Cutaneous Leishmaniasis
Initial dermal ulcer at entry site that heals; months to years later ulcers in mucous membranes of nose and mouth aris; chronic leads to erosion (disfigurement) of nasal septum, soft palate, and lips over 20-40 years. Death by secondary bacterial infections.