Card Set Information
These Drugs are what class?Plavix, effient, brilinta, ticlid, persantadine, pletal, integrillin, aggrastat
What class is plavix?
what class is effient
what class is brilinta
what class is ticlid
what class is persantadine?
what class is pletal
what class is integrillin
what class is aggrastat?
what do antiplatlets do?
prevent the aggregation of platlets
What do anticoagulants do?
prevent clot formation by inhibiting clotting factors
therefore prevent thromboembolic events
What is the main risk with anticoagulants
What lab needs to be checked with heparin and what is the therapeutic level
1.5-2.5 times the norm
normal is 30-40 secs
what is the antidote for heparin
When giving heparin how do you give it and what should you do or not do?
sq do not aspirate, massage, or rub the area of injection
What drug class are these drugs
what is lovenox
what is fragmin
what benefits do lovenox have over heparin?
no frequent lab tests, it is more stable
what is the heparin alternative for heparin induced thrombocytopenia
what drug class is coumadin and how is it administered
what drug class is pradaxa and how is it given
what drug class is xarelto and how is it given?
what is the antidote for coumadin?
what drug class comes from meds ending in ase
and what do they do?
tpa, activase, tnkase retavase, streptase, abbokinase are all what class of drugs?
what labs should be monitered when on thrombolytics?
pt, ptt, h&H platlet count
what drug class is amicar
what drug class is trasylol
what drug class is desmopresin
what drug class is digoxin
what is the action of cardiac glycosides or dig?
positive inotrope(increase the contraction of heart)
negative chronotropic effect (decrease hr)
negative dromotropic (slow conduction)
what does inotrope mean
increase or decrease in the force of contration
what does chronotrope mean
trope - increase or decrease in hr
think chrono time
increase or decrease in con
does dig increase or decrease stroke volume?
increases coronary artery perfusion
helps with chf symptoms
If a patient is on dig what do you need to assess?
b/p, pulse, heart sounds, breath sounds, weight I&O, ecg, renal function (creatnine, bun, uop) lfts
know that hypokalemia can contribute to dig toxicity
what class of drugs are nitrates
what do nitrates do
increase blood supply to heart
decrease preload, afterload and b/p
relax smooth muscle, helping with coronary artery spasms
what is preload
venous return to heart
if you have a decreased preload what does that do
decreases volume and pressure to the heart
which decreases myocardial oxygen demand
what is afterload
peripheral vascular resistance
the work the blood has to push against to get to the heart
so decreased after load is good
how can nitrates be administered?
oral, sublingual, iv, ointments, patches
what are s/e of nitrates
what is nitro used for and what by what route can it be administered?
anginal relief, iv, sl (tab or spray), topically or by patch
large first pass effect
q5 mins X3 doses
iv dose titrated as long as sbp>90
what kind of container should iv nitro be in
how long is nitro tabs good for?
how should nitro be applied
non hairy part of body with gloves, remove old patches prior to placing new patch
with nitro there should be a 8-12 nitrate free period each day to prevent tolerance, teach pt how to monitor hr and to keep a log
when giving nitro asses for
h/a, decreased b/p and dizziness
beta blocker specific for beta 1 are called
beta blockers that are for beta 1 and 2 are
what do cardioselective drugs do
decrease hr, slow conduction and decrease 02 demand (by decreasing contractility
what do the drugs end in that are beta blockers
what do nonselective beta blocker do as well as cardioselective
in addition to decreasing hr, 02 demand and slowing conduction
it also constricts the bronchiole which can lead to so
when are beta blockers used?
to decrease 02 demand
as a cardioprotective measure
atenolol carvedolol and labetolol are used to treat
hypertension and angina
metoprolol is used to treat
mi and hypertension
propranonol is non selective
nonselective used for ventricular dysrhythmias
what class is cardizen
how can cardizem be administered and what does it do?
oral and parenteral , comes in sustained release,
affinity for conduction system so it slows the hr
what drug class is verapamil
what does verapamil do and what are the forms of administration?
tx of angina
slows hr and conduction
oral and iv
when giving verapamil iv what should be done
give slowly because it can severely decrease b/p
what is ranexa
while taking anti-anginals patents should report
dizziness, fainting episodes
edema weight gain
what do ace inhibitors end in?
what do ace inhibitors do
inhibit the raas, therefore preventing the vasoconstriction and sodium and water reabsoption
what are the effects of ace inhibitors
decreased svr (afterload)
prevent sodium and water reabsorption helping chf
decreased preload (volume returning to heart)
what lab values must be monitored closely while taking ace inhibitors
potassium because it causes potassium retention
drug must be discontinued with elevated potassium
what are ace inhibitors used to treat
hf and htxn
what is minoxidil
what is apresoline
what is nipride
what do vasodilators do?
direct acting arteriolar smooth muscle relaxants
What do diuretics do
increase urine formation
remove Na+ and H2o
what do diretics tx
htxn and chf
what are the actions of diuretics
decrease co leading to decreased b/p
what do cai's (carbonic anhydrase inhibitors )tx
used as a diuretic
what do cai's do
reabsorb NA+ and H2o and release h202
what is diamox
what is lasix
what does lasix do?
loop of henley
decrease blood volume and decrease preload
while taking lasix what electrolyte is has a potential to plummet
what are umex, edecrine, demadex
what do loop diuretics tx
while taking diuretics what kind of foods should you eat?
high in K+
potatoes (especially the skin)
low in Na
what vs do you need to monitor while taking diuretics
what assesments check fluid volume status
I & O's
what are signs of hypokalemia
irregular pulse rate
wha are normal total cholesterol levels
should the goal ldl for someone with dad or diabetes be lower or higher than those without risk factors
what is niacin
lipid lowering agent
inhibits triglyceride synthesis in liver
increased uric acid secretion