BIO142

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Author:
highmonkees
ID:
145149
Filename:
BIO142
Updated:
2012-04-01 22:38:05
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Respiratory Pharmacology
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Description:
BIO142 Final Exam Review-Unit 2
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  1. The treatment of choice for pulmonary infections such as aspergillosis, histoplasmosis, and coccidioidomycosis is:

    A) Rifampin.
    B) Ampicillin.
    C) Amphotericin B.
    D) Ciprofloxacin.
    C) Amphotericin B.
    (this multiple choice question has been scrambled)
  2. A patient with HIV has been diagnosed with PCP. You are asked to recommend an antibiotic. You would suggest:

    A) pentamidine.
    B) TMP-SMX
    C) levofloxacin.
    D) tetracycline.
    B) TMP-SMX
    (this multiple choice question has been scrambled)
  3. Bupropion is an:

    A) antibiotic.
    B) anticholinergic.
    C) anxiolytic.
    D) antidepressant.
    D) antidepressant.
    (this multiple choice question has been scrambled)
  4. The use of a drug in an age group for which there is a lack of FDA-approved dosing information is termed:

    A) against the law.
    B) off-label.
    C) unapproved.
    D) orphan drug.
    B) off-label.
    (this multiple choice question has been scrambled)
  5. Inhaled pentamidine is indicated for:

    A) prevention of PCP.
    B) treatment of bronchospasm.
    C) bacterial pneumonia in cystic fibrosis patients.
    D) treatment of RSV.
    A) prevention of PCP.
    (this multiple choice question has been scrambled)
  6. Most of the agonists and corticosteroids available for inhalation have not been approved for use in person less than 18 years of age.

    True
    False
    False
  7. Smoking cessation drugs are available in which of the following forms?

    I. Gum
    II. Nasal spray
    III. Transdermal patch
    IV. IV
    V. Tablets
    I, II, III, and V only
  8. The drug used to treat hypoxic respiratory failure in newborns with pulmonary hypertension is:

    A) Xopenex.
    B) Nitric oxide.
    C) Ribavirin.
    D) Survanta.
    B) Nitric oxide.
    (this multiple choice question has been scrambled)
  9. An 80-kg male should receive what dose of Prolastin?

    A) 4800 mg weekly
    B) 2400 mg weekly
    C) 480 mg daily
    D) 240 mg daily
    A) 4800 mg weekly
    (this multiple choice question has been scrambled)
  10. Nitric oxide should not be used in neonates with:

    A) increased pulmonary artery pressure.
    B) right-to-left shunts.
    C) left-to-right shunts.
    D) pulmonary hypertension.
    B) right-to-left shunts.
    (this multiple choice question has been scrambled)
  11. Ribavirin is active against which of the following?

    I. TB organisms
    II. Influenza virus
    III. RSV
    IV. Pneumocystis carinii organisms
    V. Herpes simplex virus
    II, III, and V only
  12. Target concentration refers to drugs that are dosed until:

    A) toxicity occurs.
    B) the desired effect is achieved.
    C) a certain blood level is achieved.
    D) side effects occur.
    C) a certain blood level is achieved.
    (this multiple choice question has been scrambled)
  13. The recommended dosage of Prolastin is:

    A) 30 mg/kg once daily.
    B) 50 mg/kg once weekly.
    C) 40 mg/kg once weekly.
    D) 60 mg/kg once weekly.
    D) 60 mg/kg once weekly.
    (this multiple choice question has been scrambled)
  14. Ventilator-associated pneumonias have been successfully treated with:

    I. cephalosporins.
    II. gentamicin.
    III. tobramycin.
    IV. quinolones.
    V. penicillin.
    II and III only
  15. The recommended dose of nitric oxide is:

    A) 60 ppm.
    B) 30 ppm.
    C) 20 ppm.
    D) 40 ppm.
    C) 20 ppm.
    (this multiple choice question has been scrambled)
  16. All of the following agents can be used to pharmacologically treat smoking addiction, except:

    A) Varenicline (Chantix).
    B) Nicotine replacement patch.
    C) Bupropion (Zyban).
    D) Prolastin.
    D) Prolastin.
    (this multiple choice question has been scrambled)
  17. A dry powder inhaler is not recommended for children under the age of:

    A) 5 years.
    B) 8 years.
    C) 7 years.
    D) 12 years.
    A) 5 years
    (this multiple choice question has been scrambled)
  18. The disease that aerosolized antibiotics have been most consistently used for is:

    A) asthma.
    B) PCP.
    C) cystic fibrosis.
    D) croup.
    C) cystic fibrosis.
    (this multiple choice question has been scrambled)
  19. Aminoglycosides are used primarily for:

    A) mycoplasma infections.
    B) gram-negative infections.
    C) viral infections.
    D) gram-positive infections.
    B) gram-negative infections.
    (this multiple choice question has been scrambled)
  20. The physician suspects that your patient may have a1-antitrypsin deficiency. Which disease process would help to confirm this diagnosis?

    A) Asthma
    B) Centrilobular emphysema
    C) Bronchiectasis
    D) Panacinar emphysema
    D) Panacinar emphysema
    (this multiple choice question has been scrambled)
  21. The natural penicillins are primarily effective against:

    I. gram-negative bacteria.
    II. gram-positive bacteria.
    III. viruses.
    IV. anaerobes.
    V. mycoplasmas.
    II and IV only
  22. Relenza is a(n):

    A) corticosteroid.
    B) prophylactic agent.
    C) bronchodilator.
    D) antiviral agent.
    D) antiviral agent.
    (this multiple choice question has been scrambled)
  23. MRSA and VRE are examples of:

    A) susceptibility testing methods.
    B) new penicillin drugs.
    C) common bacterial pathogens.
    D) resistant bacterial pathogens.
    D) resistant bacterial pathogens.
    (this multiple choice question has been scrambled)
  24. The most common adverse reaction to penicillin is:

    A) nausea.
    B) seizures.
    C) headache.
    D) hypersensitivity.
    D) hypersensitivity.
    (this multiple choice question has been scrambled)
  25. Pentamidine is a(n):

    A) antiviral agent.
    B) bactericidal agent.
    C) antibiotic.
    D) antiprotozoal agent.
    D) antiprotozoal agent.
    (this multiple choice question has been scrambled)
  26. Zyban is a(n):

    A) antidepressant.
    B) bronchodilator.
    C) steroid.
    D) nicotine replacement.
    A) antidepressant.
    (this multiple choice question has been scrambled)
  27. Which group of antibiotics is effective against P. aeruginosa lung infections in CF when taken orally?

    A) Aminoglycosides
    B) First-generation cephalosporins
    C) Fluoroquinolones
    D) Antifungals
    C) Fluoroquinolones
    (this multiple choice question has been scrambled)
  28. All of the following are antimycobacterials used to treat TB except:

    A) Pyrazinamide.
    B) Gentamicin.
    C) Isoniazid.
    D) Rifampin.
    B) Gentamicin.
    (this multiple choice question has been scrambled)
  29. A drug that is used to prevent serious lower respiratory tract infections with RSV in children under 24 months of age is:

    A) NebuPent.
    B) Virazole.
    C) Intal.
    D) RespiGam.
    D) RespiGam.
    (this multiple choice question has been scrambled)
  30. The aminoglycoside antibiotics are effective in treating:

    A) gram-positive infections.
    B) mycoplasma infections.
    C) gram-negative infections.
    D) viral infections.
    C) gram-negative infections.
    (this multiple choice question has been scrambled)
  31. The approved dose of pentamidine by aerosol for prevention of Pneumocystis carinii pneumonia (PCP) is:

    A) 600 mg, once every 4 weeks.
    B) 300 mg, once every 4 weeks.
    C) 600 mg, once every other month.
    D) 300 mg, once per week.
    B) 300 mg, once every 4 weeks.
    (this multiple choice question has been scrambled)
  32. RSV-IGIV would be used to:

    A) treat active RSV infections.
    B) prevent RSV infections.
    C) treat PCP.
    D) prevent bacterial infections.
    B) prevent RSV infections.
    (this multiple choice question has been scrambled)
  33. A patient with Pneumocystis pneumonia has been systemically treated for the infection, without success. You recommend aerosolizing:

    A) Pentamidine
    B) Colistin
    C) Ribavirin
    D) Tobramycin
    A) Pentamidine
    (this multiple choice question has been scrambled)
  34. The only acceptable method of aerosolized medication delivery to a 2-year-old nonintubated patient is a nebulizer with mask.

    True
    False
    False
  35. The trade name for aerosolized pentamidine is:

    A) Atrovent.
    B) Flovent.
    C) Virazole.
    D) NebuPent.
    D) NebuPent.
    (this multiple choice question has been scrambled)
  36. Penicillins exert their pharmacological activity by:

    A) inhibiting translation of RNA into proteins.
    B) inhibiting cell wall synthesis.
    C) inhibiting protein synthesis.
    D) inhibiting DNA synthesis.
    B) inhibiting cell wall synthesis.
    (this multiple choice question has been scrambled)
  37. Tobramycin is a member of which antibiotic group?

    A) Antifungals
    B) Fluoroquinolones
    C) First-generation cephalosporins
    D) Aminoglycosides
    D) Aminoglycosides
    (this multiple choice question has been scrambled)
  38. The simplest and most common method of preparing bacteria for examination and identification is:

    A) microscopic examination of specimen.
    B) the gram stain.
    C) latex agglutination.
    D) the acid-fast stain.
    B) the gram stain.
    (this multiple choice question has been scrambled)
  39. Nicotine replacement agents are indicated to:

    A) relieve nicotine withdrawal symptoms.
    B) produce strong adverse effects of smoking.
    C) simulate the act of smoking.
    D) punish negative behaviors.
    A) relieve nicotine withdrawal symptoms.
    (this multiple choice question has been scrambled)
  40. The normal dose of ribavirin administration is:

    A) 30 mg/ml nebulized for 12 to 18 hours per day for 14 days.
    B) 20 mg/ml nebulized for 24 hours per day for 5 days.
    C) 20 mg/ml nebulized for 12 to 18 hours per day, for 3 to 7 days.
    D) 40 mg/ml nebulized for 3 to 6 hours per day, for 3 to 7 days.
    C) 20 mg/ml nebulized for 12 to 18 hours per day, for 3 to 7 days.
    (this multiple choice question has been scrambled)
  41. Systemic side effects of aerosolized pentamidine can include which of the following?

    I. Pancreatitis
    II. Conjunctivitis
    III. Neutropenia
    IV. Renal insufficiency
    V. Rash
    I, II, III, IV, and V
  42. A bactericidal agent would:

    A) kill bacteria.
    B) slow the growth of bacteria.
    C) kill bacteria, viruses, and fungi.
    D) slow the growth of bacteria, viruses, and fungi.
    A) kill bacteria.
    (this multiple choice question has been scrambled)
  43. Ribavirin is classified as a(n):

    A) antibiotic.
    B) bacteriostatic.
    C) virucida.
    D) virostatic.
    D) virostatic.
    (this multiple choice question has been scrambled)
  44. Zanamivir would be indicated for:

    A) RSV infections.
    B) exacerbation of COPD.
    C) uncomplicated influenza.
    D) cystic fibrosis.
    C) uncomplicated influenza.
    (this multiple choice question has been scrambled)
  45. Isoniazid would be indicated to treat:

    A) tuberculosis.
    B) asthma.
    C) cystic fibrosis.
    D) pneumonia.
    A) tuberculosis
    (this multiple choice question has been scrambled)
  46. Local airway side effects of aerosolized pentamidine include which of the following?

    I. Wheezing
    II. Coughing
    III. Shortness of breath
    IV. Bad taste
    V. Spontaneous pneumothoraces
    I, II, III, IV, and V
  47. Which of the following affect penetration and deposition of an aerosol in neonatal and pediatric patients?

    I. Inertial impaction
    II. Particle size
    III. Velocity
    IV. Sedimentation
    I, II, III, and IV
  48. You enter the room of your 15-month-old patient with respiratory syncytial virus (RSV) infection to deliver racemic epinephrine via SVN. His mother asks you if
    it is okay for her to give her child the breathing treatment. Because your hospital policy allows this, you agree. Five minutes into the treatment you notice that your patient's mother is holding the aerosol mask about a centimeter off of his face. You tell her:

    A) "I'll be back later...it's my lunchtime."
    B) "Good idea...he seems much more calm this way."
    C) "We need to hold the mask as close to his face as we possibly can to make sure he gets his medicine."
    D) "Maybe we should try blow-by instead."
    C) "We need to hold the mask as close to his face as we possibly can to make sure he gets his medicine."
    (this multiple choice question has been scrambled)
  49. Pentamidine is administered by aerosol with which nebulizer?

    A) Small volume nebulizer
    B) Babington nebulizer
    C) Ultrasonic
    D) Respirgard II
    D) Respirgard II
    (this multiple choice question has been scrambled)
  50. The mode of action of pentamidine is:

    A) reversal of HIV infection.
    B) buildup of immunity to Pneumocystis carinii.
    C) unknown.
    D) destruction of Pneumocystis carinii organisms.
    C) unknown.
    (this multiple choice question has been scrambled)

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