Cytokines

Card Set Information

Author:
nicstrain
ID:
14563
Filename:
Cytokines
Updated:
2010-04-14 21:58:55
Tags:
USMLE
Folders:

Description:
Cytokines - source and function
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  1. IL 1 Source
    Monocytes and macrophages
  2. IL 1 Function
    Stimulates T cell proliferation and IL2 production
  3. IL2 Source
    Macrophages, T and NK cells
  4. IL2 Function
    Stimulate proliferation of B, T and NK cells
  5. IL3 Source
    T cells
  6. IL 3 Function
    GF of tissue mast cells and hematopoietic stem cells
  7. IL4 Source
    T Cells
  8. IL4 Function
    • Increase growth of B and T cells
    • Increase HLA II Ags
  9. IL5 Source
    T cells
  10. IL 5 Function
    Maturation of B --> plasma cells
  11. IL 6 Source
    T cells, monocytes
  12. IL 6 Function
    Maturation of B and T cell / (-) fibroblasts
  13. INF alpha Source
    B cells, macrophages
  14. INF alpha Function
    Antiviral activity
  15. INF beta Source
    Fibroblasts
  16. INF beta Function
    Antiviral activity
  17. INF gamma source
    T and NK cells
  18. INF gamma function
    Antiviral activity, (+) macrophages, Increase HLA II Ags
  19. TNF alpha Source
    Macrophages, T and NK cells
  20. TNF alpha Function
    T cell proliferation IL2 production, cytotoxicity
  21. TNF beta source
    T cells
  22. TNF beta function
    T cell proliferation IL2 production, cytotoxicity

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