Parkinsons disease and cortex and lesions
increased activity that is responsible for clinical abnormalities, in the STN
correcting activity in STN or GP can correct problems
lesions--surgical lesions in GP, decreases PD features on the opposite side, right by the internal capsule which contains the corticospinal pathways, and if these are affected you can get a UMP lesion which is irreversible
stimulatin the structure has the same effect as a lesion, STN electordes emplanted while awake.