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What is epidemiology?
the statistical study of patterns of disease in a population
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What is delusion?
a false belief strongly held in spite of contrary evidence
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What is schizophrenia?
a severe psychopathology characterised by negative symptoms such as emotional withdrawal and impoverished thought, and by positive symptoms such as delusions and hallucinations.
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What is dissociative thinking?
a condition, seen in schizophrenia, that is characterised by disturbances of thought and difficulty relating events properly.
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What are positive symptoms?
hallucinations, delusions, excited motor behav
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What are negative symptoms?
emotional and social withdrawal, blunted affect, slowness, impoverishment of thought and speech
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What are monozygotic twins? Dizygotic?
mono are twins from a single egg. dizygotic are twins from two eggs. mono=identical twins, di=fraternal twins
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What is concordent? discordent?
- concorden=both ppl in set of twins share the trait
- discordent=one person in set of twins has trait
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What is the hypofrontality hypothesis?
schizophrenia may reflect underactivation of the frontal lobes
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What is amphetamine psychosis?
a delusional state resembling schizophrenia from repeated use of high doses of amphetamine
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What is chlorpromazine?
an antipsychotic drug, one of the class of phenthiazines.
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What are phenothiazines?
a class of antipsychotic drugs that reduce the postive symptoms of schizophrenia
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what are neuroleptics or antipsychotics?
drugs alleviating symptoms of schizo by blocking dopamine receptors
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what are typical neuroleptics?
a major class of schizo drugs that share antagonist activity at dopamine D2 receptors.
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What is the dopamine hypothesis?
schizo results from excessive levels of synaptic dopamine or excessive post synaptic sensitivity to dopamine.
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What are atypical neuroleptics?
a class of antischizophrenic drugs with actions other than antagonist activity at D2 receptors (typical neuroleptics). An example is clozapine.
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What is clozapine?
an atypical neuroleptic
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What is phencyclidine? (PCP)?
anesthetic agent thats also a psychedelic drug. Causes dissociation from yourself and environment.
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What is a psychotomimetic?
a drug inducing a state similar to schizophrenia
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what is the glutamate hypothesis?
that schizophrenia might be caused partly by the understimulation of glutamate receptors
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What is depression? (symptoms)
a condition with unhappy mood, loss of interest energy and appetite and difficulty concentrating
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What is unipolar depression?
depression that alternates with normal emotional states
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what is electroconvulsive shock therapy? (ECT)
last resort treatment for depression where a electric current passes through the brain causing a seizure
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What is monoamine oxidase (MAO)?
an enzyme that breaks down and thereby inactivates monoamine transmitters
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What is reserpine?
a drug that causes the depletion of monoamines and can lead to depression
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what are selective serotonin reuptake inhibitors?
a drug that blocks the reuptake of transmitter at serotonergic synapses, used to treat depression
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