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- Resistance/protection from an individual's environment
- Primarly: 'chemical system'
- Also cell-mediated: T-cells & B-cells
- Antigen -vs- antibody response
- Any substance foreign to the host
- Complete: induces immune response & reacts w/antibodies
- Incomplete or 'hapten': reacts w/antibody. But does NOT elicit immune response w/o being coupled w/another antigen or cell.
- Substance raised in self as an antagonist to the antigen.
- Immuoglobulins: family of 'serum proteins'
- Produced in plasma cells
- (* B-cells: lymphocytes capable of producing antibody)
- B-cells: originate in bone marrow & lymphoid tissue of the alimentary tract.
- Lymphocytes that mature in the thymus
- Four different types: T-helper; T-suppressor; Cytotoxic T-cells; & Natural Killer cells
Delivers antigen to B-cell
Diminishes excess antibody production
Kill cells that process foreign/altered antigens.
"Natural Killer cells"
- Capacity to spontaneously kill various target cells
- Capable of binding to & killing virus-infected & tumor cells.
- Mechanism not understood
* Process of Immunity
- Reticular Endothelial (RE cells): break down antigens
- 1) 'monocyts' & 'macrophages': their presence stimulates lymphocyte production.
- Pieces are presented to T-cells