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Nervous System consists of the __NS and the __NS.
C(Central) and P(Peripheral)
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CNS; 3 parts
- 1. Brain
- 2. Spinal Cord
- 3. Neuroglial Cells
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Neuroglial Cells are ...
CNS support cells
they cannot conduct action potential
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PNS; 4 parts
- 1. Somatosensory Nervous System
- 2. Cranial Nerves
- 3. Autonomic Nervous System (visceral motor)
- 4. Enteric
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Somatosensory
Sensory and Motor (voluntary)
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Cranial Nerves
12 total nerves
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Autonomic Nervous System; 2 Divisions
- 1. Sympathetic
- 2. Parasympathetic
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Sympathetic division
fight or flight responce
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Parasympathetic division
rest and digest responce
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What does a Neuron do?
- AKA Nerve
- conducts an action potential
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The Neuron consists of; 5 parts
- 1. Receptors
- 2. Dendrites
- 3. Soma
- 4. Axon
- 5. Synaptic Knob
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Receptors are?
modified dendritic endings
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Dendrite is?
primary site for recieving signals, resembles bare branches of a tree
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Soma is known as ?
The body of a nerve cell and the decision maker
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Soma consists of ? 3 parts
- 1. Nucleus & Nucleolus
- 2. parikaryon with Nissl Bodies
- 3. Grey Matter
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Nucleus and Nusleolus do what?
Make a decision
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Perikaryon is
The cell body
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Nissl Bodies are?
bundles of ribosomes that make some proteins and neurotransmitters
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Grey Matter
is Hydrophillic, indicates nerve cell bodies due to having nissl bodies
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Axon ?
- hillock
- terminals
- Myelin Sheath
- Schwann/neurolemmal cells
- Nodes of Ranvier
- *conducts action potential
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describe an axon hillock
is the beggining of the axon and starts the action potential
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axon terminals
the branches at the end of an axon that have synaptic knobs at the end of them
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Myelin Sheath is?
a fatty insulater; type of nerve fiber
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Schwann cells
make myelin in layers to form the Myelin Sheath
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neurolemmal cells
is the last layer of myelin produced by a schwann cell and has the nucleus in it
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Nodes of Ranvier is the?
unmyelinated gaps between neurolemmal cells
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2 types of action potential conduction?
- 1. Saltatory Conduction
- 2. Continuous Propagation
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Saltatory Conduction
Only occurs on Myelinated Nerves, is extremely fast, the action potential appears to jump from Node to Node of Ranvier
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Continuous Propagation
occurs only on nonmyelinated nerves, is slower, voltage gated channels along cell open and close in a series as the action potential moves along
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Synaptic Knob
some neurotransmitter are stored here and are released when action potential reaches it
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Structural classification of a nerve cell; 4 types
- 1. Unipolar
- 2. Bipolar
- 3. Multipolar
- 4. Anaxonic
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Unipolar
has only one distinctive axon; somatosensory neuron located in DRG(Dorsal Root Ganglion)
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Bipolar
has two distinct axons; located in the retina of the eye
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Multipolar
has many poles but only one distinct axon; alpha motor neurons located in anterior motor horn
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Anaxonic
has many poles and no axon; interneurons of CNS
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The Synapse; 3 parts
- 1. Presynaptic Neuron
- 2. Synaptic Cleft
- 3. Postsynaptic Neuron
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Presynaptic Neuron
transmittes nerve impulse by releasing neurotransmitters into cleft
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Synaptic Cleft
is the space between 2 neurons
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Postsynaptic Neuron
recieves the nerve impulse as neurotransmitters
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Action Potential; 3 steps
- 1. Polorized aka resting potential
- 2. Depolarized aka action potential
- 3. Repolarization
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Polarized
is when there is a negatively charged cell -70mV has a threshold of -60mV when the Gates open
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Depolarization
is when there is a rush of positively charged sodium ions(Na+) inside cell bringing the internal charge to +30mV
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Repolarization 2 changes
- 1. Hyperpolarization
- 2. Sodium/Potassium Pump
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Hyperpolarization
is when there is a rush of positively charged potassium ions(K+) outside cell bringing the internal charge to -90mV
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Sodium/Potassium Pump
is the gradual exchange of sodium ions out of cell and potassium ions into cell until the cell is polarized with an internal charge of -70mV
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Neuroglial cells are? 3 cells; and do?
- 1. Microglial Cells
- 2. Ependymal Cells
- 3. Astrocytes
- 4. Oligodendrocytes
support cells of CNS
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Microglial cells
are immune cells(phagocytes) that remove waste and toxins; eat
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Ependymal Cells
occur in clusters located in the choroid plexus and produce CSF(Cerebral Spinal Fluid)
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Astrocytes
make up the Blood Brain Barrier to prevent bacteria and viruses from entering the CNS
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Oligodendrocytes
Make Myelin in the CNS
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Meninges is the? and is made up of 3 layers?
protective tissue around the CNS
- 1. Dura
- 2. Arachnoid
- 3. Pia
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Dura layer
outermost layer of the meninges, strong
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Arachnoid layer
spider web like tissue that contains CSF(Cerebral Spinal Fluid) in the Subarachnoid Space; creates a cushion against movement
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Pia
intimately attached to CNS, is form fitting
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Meningitis bacterial
treat with antibiotics
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Meningitis viral
palliative care/ wait it out
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Meningitis c/o
stimuli senstitive
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test for Meningitis
ortho test/SOTO HALL- pain in back of neck, old test
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CSF(Cranial Spinal Fluid) path (8)
- 1. secreted by choroid plexus in each lateral ventrical
- 2. into third ventrical
- 3. third ventrical choroid plexus adds fluid
- 4. into fourth ventrical
- 5. fourth ventrical choroid plexus adds more fluid
- 6. flows through 3 apertures
- 7. fills subarachnoid and spinal canal
- 8. at arachnoid granualations absorbed into blood
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Hydrocephalus
CSF(Cranial Spinal Fluid) build up/ swelling
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encephalitis
nerves infected; ex. west nile
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Spinal Cord & Nerves; 9 topics
- 1. Ganglion
- 2. plexus
- 3. 31 pairs of spinal nerves
- 4. Cervical Enlargement
- 5. Intercostal Nerves
- 6. Lumbar Enlargement
- 7. Conus Medularis
- 8. Cauda Equina
- 9. Filum Terminale
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Ganglion is
a group of nerve cell bodies; appears as fat area in nerve
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Plexus is
a group of nerve fibers/axon & dendrites
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Cervical Enlargement has 2 plexus
- 1. Cervical Plexus
- 2. Brachial Plexus
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Cervical Plexus has
Phrenic Nerve which intervates the diaphragm
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Brachial Plexus has 3 nerves
- 1. Radial Nerve
- 2. Median Nerve
- 3. Unlar Nerve
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Radial Nerve controls
wrist extensors and thumb
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Median Nerve controls
wrist flexors
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Ulnar Nerve controls
Pinky
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Intercostal Nerves are
located between ribs assist in breathing
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Shingles affects
DRG(Dorsal Root Ganglion) sensory of intercostal nerves
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Polio affects
anterior motor horn or alpha motor neuron and causes paralysis
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Lumbar Enlargement has 2 plexus
- 1. Lumbar Plexus
- 2. Sacral Plexus
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Lumbar Plexus consists of 3 Nerves
- 1. Obturator Nerve
- 2. Femoral Nerve
- 3. Tibial Nerve
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Obturor Nerve controls
adductor group/medial thigh
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Femoral Nerve controls
knee extensors/quads; front of thigh/knee; L4
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Tibial Nerve controls
knee flexors/hamstrings
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Sacral Plexus consists of one Nerve
Sciatic Nerve aka sciatica
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Sciatic Nerve controls
- Hamstrings
- peroneal/fibular nerve/calf muscles plantor flexors
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Conus Medularis is
where spinal cord ends; near L2
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Cauda Equina is
the spinal nerves that continue down spinal canal inferior to conus medularis
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Filum Terminale is
the terminal ligaments end of meninges which attaches to coccyx
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Spinal tap/ lumbar puncture occurs at
L4
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Spinal Cord Cross Section includes 6 parts
- 1. Spinal Nerve
- 2. Dorsal Root Ganglion
- 3. Grey H
- 4. Columns
- 5. Denticulate Ligament
- 6. Central Canal
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Spinal Nerve is
a mixed nerve
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Dorsal Root Ganglion is
a sensory nerve cell/somatosensory nerve cell
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Grey H contains 2 pairs of horns and in the center is
- 1. Anterior Motor Horn
- 2. Lateral Horn
Interneuron
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Anterior Motor Horn has
Alpha Motor Neurons
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Lateral Horn has
sympathetic nerve cell bodies
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Interneurons are
association neurons that provide and gather information
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