Rocuronium

Non depolarizing neuromuscular blocking agent

Non depolarizing neuromuscular blocking agent with rapid to intermediate onset. Depending on dose intermediate duration of action

Acts by binding competitively to cholinergic receptors at the motor end plate to antagonize the action of ACh, an effect that is reversible in the presence of acetylcholinesterase inhibitors such as neostimine & edrophium

• Onset: 30-60 sec
• Peak: 1-3 min
• Duration: 30-60 min
• Half-life: 14-18 min

adjunct to general anesthesia to initiate ET intubation & provide skeletal muscle relaxation during surgery or mechanical ventilation

Known hypersensitivity

• Administer in carefully adjusted doses
• Slight elevation in HR & BP
• Tachycardia in pedi

Bronchospasm

• 0.6 mcg/kg for RSI up to 600mcg
• Maintenance dose 0.1-0.2 mcg/kg up to 100-200 mcg continuous infusion

0.6 mcg/kg for RSI up to 600mcg

As needed

IV/IO

Vials