practice calculating renal clearance: if plasma (creatinine) is 4 mg/mL, urine (creatinine) is 120 mg/mL, and urine flow rate is 1 mL/min, what is the renal clearance:
given that a nrmal GFR is 125 mL/min and based on your clacluation above, is this new drug secreted or reabsorbed by the nephron?
U ( creatinine concentration in urine) x V (rate of urine output) / P (creatinine concentration in plasma)
120 x 1/4 = 30mL/min
RPC < GFR = substance is absorbed