top drugs 71-92.txt

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HUSOP2014
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147933
Filename:
top drugs 71-92.txt
Updated:
2012-04-16 14:47:33
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HUSOP 2014 LAB TOP
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Description:
2014 4C LAB Top Hospital drugs
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  1. Enbrel
    • Gen: Etanercept
    • Class: Immune Suppressant (TNFalpha inhibitor)
    • RoA: SC
    • MOA: Binds to TNFa,b receptor inactivation inflammatory/ immune response, and other cytokines
    • Indication: RA, Juvenile Idiopathic arthritis, Psoriasis
  2. Magnevist
    • Gen: Gadopentetate Dimeglumine
    • Class: Non-ionic contrast media
    • RoA: IV
    • Indication: Diagnostic Radiology
  3. Argatroban
    • Gen: Argatroban
    • Class: Anticoagulant
    • RoA: IV
    • MOA: binds active thrombin site to inhibit
    • Indication: Coronary Artery Thrombosis, Heparin-induced Thrombocytopenia
  4. Thymoglobulin
    • Gen: Lymphocyte Immune Globulin
    • Class: Immune Supressant
    • RoA: IV
    • MOA: Clears and suppresses T-cell activation
    • Indication: Renal transplant rejection (adjunct)
  5. Novolog
    • Gen: Insulin Aspart, Recombinant
    • Class: Antidiabetic (rapid acting insulin)
    • RoA: SC
    • MOA: binds insulin receptors on muscle and fat cells to increase glucose uptake
    • Indication: Diabetes mellitus types 1 & 2
  6. Ambisome
    • Gen: Amphotericin B Liposome
    • Class: Antifungal (polyene)
    • RoA: IV
    • MOA: binds to ergosterol in cell membranes causing permeability, leaking and cell death
    • Indication: fungal infections (aspergillosis, candidiasis, meningitis-HIV, pumonary aspergillosis)
  7. Cipro
    • Gen: Ciprofloxacin
    • Class: Antibiotic (Fluoroquinolone)
    • RoA: IV, Oral
    • MOA: Interference of DNA gyrase(DNA synthesis)
    • Indication: bacterial infections (Anthrax, gonorrhea, bronchitis, nosocomial pneumonia, LRTI, UTI)
  8. Sandostatin Lar
    • Gen: Octreotide Acetate
    • Class: Somatostatin (Endocrine-metabolic agent)
    • RoA: SC, IV, IM
    • MOA: reduces growth hormone, LH, GnRH
    • Indication: Acromegaly, Carcinoid Syndrome, Vasoactive Intestinal Peptide-Secreting Tumor
  9. Keppra
    • Gen: Levetiracetam
    • Class: Anticonvulsant
    • RoA: IV, Oral
    • MOA: prevents hypersynchronization of epileptiform burst firing and propagation
    • Indication: Partial, Myoclonic, Tonic-clonic Seizures
  10. Albuminar-25
    • Gen: Albumin Human
    • Class: Volume Expander
    • RoA: IV
    • MOA: increases volume and plasma
    • Indication: ARespiratory Distress, Ascites, Burns, liver failure, Nephropathy, Pancreatits
  11. Botox
    • Gen: Onabotulinumtoxin-A
    • Class: Musculoskeletal agent, Botulinum Toxin Type A
    • RoA: IV, IM
    • MOA: blocks neuromuscular conduction on motor nerve terminals, inhibiting acetylcholine release
    • Indication: Blepharospasm, headache, hyperhidrosis of axilla, incontinence (detrusor instability), strabismus, upper limb spasticity, wrinkled face
  12. Venofer
    • Gen: Iron Sucrose
    • Class: Parenteral Mineral-Trace Mineal
    • RoA: IV
    • MOA: dissociates to iron and sucrose components, increases iron, ferritin levels, decreases total iron binding capacity
    • Indication: Iron deficiency anemia
  13. Paclitaxel
    • Gen: Paclitaxel
    • Class: Antineoplastic agent, Mitotic Inhibitor
    • RoA: IV
    • MOA: enhances the cytotoxic effects of ionizing radiaion
    • Indication: Breast, Ovarian, small cell lung cancer, AIDS-related Kaposi's sarcoma
  14. Effexor XR
    • Gen: Venlafaxine Hydrochloride
    • Class: Antidepressant (phenethylamine- SNRI)
    • RoA: Oral
    • MOA: inhibits 5HT, NE, Da reuptake
    • Indication: GAD, MDD, Panic disorder, Social Phobia
  15. Neurontin
    • Gen: Gabapentin
    • Class: Anticonvulsant (GABA enhancement)
    • RoA: Oral
    • MOA: increases GABA
    • Indication: Partial Seizure, Postherpetic Neuralgia
  16. Aloxi
    • Gen: Palonosetron Hydrochloride
    • Class: Antiemetic (5HT3 antagonist)
    • RoA: IV
    • MOA: inhibits the vomiting reflex
    • Indication: Chemotherapy-induced N/V
  17. Gardasil
    • Gen: Human Papillomavirus Vaccine
    • Class: Vaccine
    • RoA: IM
    • MOA: develops humoral immune response against paps 6, 11, 16, and 18.
    • Indication: viruses associated with cancer treatment
  18. Trasylol
    • Gen: Aprotinin
    • Class: Hemostatic
    • RoA: IV
    • MOA: unknown but maintains platelet function, prevents fibrinolysis
    • Indication: Hemorrhage (surgery)
  19. Xigris
    • Gen: Drotrecogin Alfa
    • Class: Anticoagulant, Profibrinolytic
    • RoA: IV
    • MOA:
    • Indication: Sepsis syndrome from organ dysfuction (pulled from market)
  20. Glucophage
    • Gen: Metformin Hydrochloride
    • Class: Biguanide, Hypoglycemic
    • RoA: Oral
    • MOA: 1. decreases hepatic glucos production
    • 2. decreases intestinal absorption,
    • 3. increases peripheral glucose uptake
    • 4. improves insulin sensitvity
    • Indication: Diabetes Mellitus type 2
  21. Xopenex
    • Gen: Levalbuterol
    • Class: Bronchodilator (Beta-2 agonist)
    • RoA: Inhalation
    • MOA: relaxation of airway SM
    • Indication: Asthma
  22. Prograf
    • Gen: Tacrolimus
    • Class: Antipsoriatic, Immune Suppressant, Calcineurin Inhibitor
    • RoA: IV, Oral, topical
    • MOA: Inhibits T-lymphocyte activation, and other cytokines
    • Indication: transplant rejection, atopic dermatitis

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