Dobutamine

Sympathetic Agonist

Synthetic Catecholimine that primarily acts on Beta 1 receptors but is less potent than isoproterenol

• Increases the force of systolic contraction with little chronotropic activity.
• Useful in management of CHF when increased HR is not desired.

• Onset: 2-10 min
• Peak: 10-20 min
• Duration: Varies
• Half-life: 2 min

CHF when increase CO without increased HR is desired

Hypovolemic shock when fluid resuscitation is not well underway

• Tachycardia and an increase in systolic BP
• Increases in HR more than 10% induce or exacerbate myocardial ischemia.
• PVC's can occur in conjunction with administration
• Monitor BP
• May be ineffective for pts on beta blockers

• Tachycardia
• Palpitation
• Dysrhythmia
• Hypertension
• Chest pain
• Nervousness
• Nausea
• Vomiting

2-20mcg/kg/min

2-20mcg/kg/min

20mcg/kg/min

IV/IO

Vials