state how iron can be involved in pigmentation and the possible outcomes
excess iron initially stored as ferritin, with further accumulation of intracellular iron, ferritin molecules aggregate to produce a crystallin yellow-brown pigment hemosiderin). Localized deposition of hemosiderin is due to hemorrhage at site of pigmentation, commonly seen in relation to bruises. Excess hemosiderin is deposited in parenchyma and reticuloendothelial system. Accumulation of excess iron can be due to increased absorption of iron, decreased excretion, impaired utilization, excess breakdown of hemoglobin with release of iron.