Card Set Information
Cancer cells must:
identifies preventable causes
(prevention is better than cure)
permanent change in a cell's DNA; includes changes in nucleotide seq., alteration of gene position, gene loss or duplication, and insertion of foreign seq.
Dominant vs Recessive mutation:
: gain of function
: loss of function
the unrestrained growth and division of cells, reults in failure of cell division control.
a mutant form of a growth regulating gene that is inappropriately 'ON' , causing unrestrained cell growth and division.
a normal cellular gene that can act as an oncogene when mutated.
neoplasm [a solid or fluid-filled (cystic) lesion that may or may not be formed by an abnormal growth of neoplastic cells] that appears enlarged in size
migration of cancerous cells
benign vs cancerous tumor
benign tumor:lacks ability to metastyze (moles)
canceroues - migrates
A carcinogen is any substance, radionuclide, or radiation that is an agent directly involved in causing cancer.
is a physical or chemical agent that changes the genetic material, usually DNA, of an organism and thus increases the frequency of mutations
As many mutations cause cancer, mutagens are therefore also likely to be carcinogens.
or anti-oncogene, is a gene that protects a cell from one step on the path to cancer.
Genetic changes convert proto-oncogene into an oncogene: