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ACTIVATED CHARCOAL (Actidose)
- Description: Is a specially prepared charcoal that will adsorb and bind toxins from the gastrointestinal tract.
Indications: Acute ingested poisoning
Precautions: Administer only after emesis or in those cases where emesis is contraindicated.
Dosage/Route: 1G/Kg mixed with at least 6 to 8 oz of water, then PO or via an NG tube
Description: Naloxone is a pure narcotic antagonist that blocks the effects of both natural and synthetic narcotics and may reverse respiratory depression.
Indications: Narcotic and synthetic narcotic overdose, coma of unknown origin.
Contraindications: Hypersensitivity to the drug, non–narcotic-induced respiratory depression.
- Precautions: Possible dependency (including newborns). It also has a half-life that is shorter than that of most narcotics; hence the patient may return to the overdose state.
- Dosage/Route: 0.4 to 2 mg IV/IM/IN repeated/2 to 3 min as needed up to 10 mg.
- Pedi: 0.01 mg IV/IM repeated/2 to 3 min as needed up to 10 mg.
- Description: Flumazenil is a benzodiazepine antagonist used to reverse the sedative, recall, and psychomotor effects of diazepam, midazolam, and the other benzodiazepines.
- Indications: Respiratory depression secondary to the benzodiazepines.
- Contraindications: Hypersensitivity to flumazenil or benzodiazepines; those patients who take medication for status epilepticus or seizures; seizure-prone patients during labor and delivery; tricyclic antidepressant overdose.
- Precautions: Hepatic impairment, elderly, pregnancy, nursing mothers, head injury, alcohol and drug dependency and physical dependence on benzodiazepines.
- Dosage/Route: 0.2 mg IV over 30 sec/min, up to 1 mg.