Antidote Drugs

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    - Absorbent

    - Description: Is a specially prepared charcoal that will adsorb and bind toxins from the gastrointestinal tract.

    Indications: Acute ingested poisoning

    Precautions: Administer only after emesis or in those cases where emesis is contraindicated.

    Dosage/Route: 1G/Kg mixed with at least 6 to 8 oz of water, then PO or via an NG tube
  2. NALOXONE (Narcan)
    Narcotic Antagonist

    Description: Naloxone is a pure narcotic antagonist that blocks the effects of both natural and synthetic narcotics and may reverse respiratory depression.

    Indications: Narcotic and synthetic narcotic overdose, coma of unknown origin.

    Contraindications: Hypersensitivity to the drug, non–narcotic-induced respiratory depression.

    • Precautions: Possible dependency (including newborns). It also has a half-life that is shorter than that of most narcotics; hence the patient may return to the overdose state.
    • Dosage/Route: 0.4 to 2 mg IV/IM/IN repeated/2 to 3 min as needed up to 10 mg.
    • Pedi: 0.01 mg IV/IM repeated/2 to 3 min as needed up to 10 mg.
  3. FLUMAZENIL (Romazicon)
    Benzodiazepine Antagonist

    - Description: Flumazenil is a benzodiazepine antagonist used to reverse the sedative, recall, and psychomotor effects of diazepam, midazolam, and the other benzodiazepines.

    - Indications: Respiratory depression secondary to the benzodiazepines.

    - Contraindications: Hypersensitivity to flumazenil or benzodiazepines; those patients who take medication for status epilepticus or seizures; seizure-prone patients during labor and delivery; tricyclic antidepressant overdose.

    - Precautions: Hepatic impairment, elderly, pregnancy, nursing mothers, head injury, alcohol and drug dependency and physical dependence on benzodiazepines.

    - Dosage/Route: 0.2 mg IV over 30 sec/min, up to 1 mg.
Card Set
Antidote Drugs
Medic 13 Antidotes
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