Pharmacology

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cfr
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14973
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Pharmacology
Updated:
2010-04-17 22:10:34
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Pharmacology
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  1. This slows conduction through AV node, interrupts AV nodal reentry pathways & restores NSR in PSVT. Half life is < 10sec due to red blood cell sequestering
    Adenosine
  2. Sympathomimetic that is relatively selective for Beta 2 adrenergic receptors.
    Bronchodilator with few cardiovascular effects
    Duration 4-6 hrs
    Albuterol
  3. Class IIb Antidysrhythmic for ventricular dysrhythmias.
    Prolongs action potential duration in all cardiac tissues
    Amiodarone/Cordarone
  4. NSAID that inhibits platelet Aggregation
    Aspirin
  5. Parasympatholytic
    Enhances sinus node automatacity and AV conduction via vagolytic action
    Atropine
  6. Dextrose is fuel for cellular metabolism and is regulated by insulin
    D50
  7. Benzodiazepine sedative
    Acts as a tranquilizer, anticonvulsant, and skeletal muscle relaxant (via CNS)
    Diazepam/Valium
  8. Reverses effects of phenothiazines and has anticholinergic and antiemetic effects
    Antihistamine
    Diphenhydramine
  9. Beta 1 receptor with positive inotropic and negative chronotropic effects
    • Dopamine
    • inotropic = muscle force
    • chronotropic = heart rate
  10. Beta stimulator with positive chronotropic and inotropic effects.
    Epinephrine
  11. Relaxes smooth muscle of the bronchi and is therefore effective in treating bronchoconstriction associated with asthma and anaphylaxis
    Epi 1:1K
  12. Increases blood flow to heart during CPR
    EPI 1:10K
  13. 50-100 times more potent than Morphine with shorter duration of action. Principal therapeutic values are analgesic and sedative
    Resp rate and alveolar ventilation changes might last longer than analgesic effect.
    Onset is immediate
    Fentanyl
  14. Inhibits reabsorbtion of sodium and chloride in kidney, producing peak diuresis. Rapidly reduces extracellular fluid, decreases venous return and ventricular output by causing venous dilation (3-4min).
    Furosemide
  15. Sympathomimetic that is selective for Beta 2 adrenergic receptors.
    Causes relaxation of bronchial smooth muscle, thus decreases airway resistance and increases vital capacity.
    Greater affinity for B2 adrenergic receptors than its chemical variant
    Levabuterol/Xopenex
  16. Increases Fibrillation threshold of myocardium and decreases automatacity, supressing ventricular ectopy.
    Decreases stimulation of CNS during intubation
    Lidocaine
  17. Has selective Beta 1 adrenergic receptors.
    Decreases HR, systolic BP, and Cardiac output
    Effective in reducing incidence of V-Fib & Chest pain in MI patients.
    Metropolol
  18. Benzodiazepine sedative
    Acts as a amnesic, hypnotic, antiolytoc, and anticonvlsant
    3-4 times more potent than other benzodiazepine
    Midazolam/Versed
  19. Potent analgesic
    Reduces anxiety associated with pain (important in cardiac related pain)
    CNS depressant, increases peripheral venous capacity
    Decreases venous return, decreases myocardial demand
    Morphine
  20. Narcotic antagonist that binds with narcotic receptor sites
    Narcan
  21. Nasal decongestant that causes vasoconstriction of superficial blood vessels in nasal mucosa
    Neosynephrine
  22. Smooth muscle relaxant causing vasodilation.
    Decreases cardiac preload.
    May improve perfusion t ischemic myocardium by dilating coronary arteries.
    May provide a significant degree of pain control in patients with cardiac chest pain
    Nitroglycerin
  23. Reduces the workload on the hear and lungs to maintain proper perfusion.
    Facilitates breakdown of glucose into a usable energy for to maintain aerobic metabolism
    Oxygen
  24. Alkalizing agent that binds with excess ions to correct metabolic acidosis
    Sodium Bicarbonate
  25. Synthetic adrenal corticosteroid used as an antiinflammatory in spinal injury and in the management of acute and chronic inflammatory diseases.
    Inhibits inflammatory response by interfering with many of the substances that cause inflammation (cytokines, interleukin, interferon)
    Solu-Medrol
  26. This is required for the conversion of pyruvic acid to acetyl coenzyme A.
    With out this a significant amount of energy available in glucose cannot be obtained.
    • Thiamine B1
    • Any comatose patient (especially those suspected to be alcoholic) should receive thiamine in addition to D50 or Narcan
  27. A naturally occuring anti-diuretic hormone which becomes a powerful vasoconstrictor when used at a higher dose than normal.
    Exerts a greater vasoconstrictive effect under conditions of hypoxia and acidosis than its co-drug. It also lasts longer, has greater arterial tone, and therefore, has an effect that correlates with greater myocardial perfusion.
    It does not increase myocardial oxygen consumption and lactate production in the arrested heart.
    Vasopressin
  28. This has mild sedative properties, is tolerated well in pediatric populations, is safe in pregnancy, and does not produce extrapyramidal effects of phenothiazines.
    Serotonin 5-HT3 receptor antagonist antiemetic
    Ondansetron/Zofran

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