Patho chapter 18

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tville01
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151103
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Patho chapter 18
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2012-04-30 08:51:04
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Patho chapter 18
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Patho chapter 18
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  1. Any disease that narrows the coronary arteries
    Coronary Artery Disease /CAD
  2. General term for all types of arteriole changes
    Thickening, loss of elasticity & calcification of arteriole walls
    Leads to narrow lumens, ishemia, & necrosis
    Arteriosclerosis
  3. Form of arteriosclerosis
    Presence of artheromes
    Thickening and hardening of the arteries due to lipid, fibrin, debris, and thrombus hardening
    Atherosclerosis
  4. What are the general effects of Artheroclerosis?
    • Decrease perfusion of organs
    • Increase platelet adhesion
    • promotes the development of aneurysm
  5. How does an atheroma begin to form?
    endothelial injury to an artery, which rasises C-reactive proteins
  6. What is the earliest atheroma lesion?
    fatty streak
  7. What do fatty streaks consist of?
    • lipid filled smooth muscle
    • macrophages
  8. Thin yellow discolorations of artery tunica intima that progressively enlarge over time
    Fatty streak
  9. What are the characteristic lesion of advancing athersclerosis?
    plaque
  10. blood levels high in LDL and cholesterol
    hyperlipidemia
  11. Where do thrombuses usually form
    biofurcations of large arteries(aorta, coronary, carotid, illiac)
  12. What are the consuqences of arthersclerosis?
    • Athermoas
    • Myocardial Ischemia
    • Myocardial Infarction(Heart Attack)
  13. Intermittent periods of Ischemia
    Cardiac muscles are alive, but unable to function normally
    Myocardial Ischemia
  14. Heart attack
    Death of Cardiac muscle
    Occurs when Ischemia is over 20 minutes
    Myocardial Infarction
  15. What are the risk factors for CAD?
    • Hyperlipidemia
    • Hypertension
    • Smoking
    • Diabetes
    • Genetic
    • Age
    • Gender
    • Obesity
    • Sedentary Lifestyle
  16. Localized contraction of arteriolar smooth muscle
    vasospasm

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