Describe a Class I drug for disrhytmias. Prototype?
Lidocaine: Na+ channel blocker
What is the main indicator for Lidocaine, a class 1 anit-dysrhythmic drug? When is it administered?
Ventricular dysrhythmias; during the peri-infarct period during cardiac arrest situations
What is the MOA for a class III dysrhythic durg? Prototype?
Amiodarone: blocks K+ channel to disrupt repolarization
What is the general MOA for disrhythmic drugs?
Disrupt ion movement
Why do we use cardiac rhythm drugs?
After attempts to treat the underlying problem have failed. Ex; if the heart is off b/c of hyperkalemia, treat the hyperkalemia first.
What are three side effects of dysrhythmic drugs?
Bradycardia, conduction delay leading to hemodynami instability (ciruclation), and prodysrhythmia (it can actually make the problem worse)
What is the infusion rate for Lidocaine?
Rapid infustion over 1 -2 minutes
How do you reember Amiodarone?
Ami & Darone Both (works on supravent/ventricle) Have (hypotension) 3 (class III ACLS) Blind (optic neuropathy, photosensitivity, corneal deposits)Pigs (pulmonary fibrosis) with Liver problems (hepatic dysfunction).
What is the main indication for Adenosine?
What is unique about the location and infustion rate of Adenosine?
As near to the heart as possible; supre fast (in seconds) because the half-life is only seconds long.
What is the goal of Adensoine?
Asystole, hopefully the heart can then get a normal rhythm
Who will be around when adenosine is administered?
The Code Team!
What sides effects are associated with Adenosine?
No. Except death if the pt doesn't come back from asystole.