Path Last Min

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HLW
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152005
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Path Last Min
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2012-05-03 19:41:38
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Path Last Min
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  1. Death of a neuron leads to…
    • Eosinophilia
    • Karyohexis
  2. Lipid laden Macs are called fat granule cells of ______ their nuclei are _____
    • GITTER CELLS
    • ENLARGED & ECCENTRIC
  3. _____ & ____metaplasia is seen in old dogs an an ovoid, thin to whitish mottled red. It is an INCIDENTAL finding and not IVD
    Cerebral and Spinal dural ossesous
  4. Encephalocele- 4 characterisitcs
    • Protrusion of brain and meninges thru defect in cranium (crania bifida)
    • They are related to the suture line &
    • Almost always median
    • Skin forms the hernia sac
  5. CNS Bacterial Inflammation : 4
    • Vascular Response
    • Perivascular Cuffing
    • Neural Degen/Death
    • Gliosis
    • (rarely demyelination)
  6. Lissencephaly (agyria)=
    smooth brain convolutions are almost entirely absent 

  7. Hydracephaly-
    almost complete absence of the cerebral hemisphere leaving only membranous sacs filled with CSF and enclosed leptomeninges the cranial cavity is ALWAYS complete 

  8. Cerebellar Atrophy-
    premature or accelerated degeneration or formed elements by some intrinsic metabolic defect
  9. 
Syringomyelia-tubular cavitation of the spinal cord it is rare except in the weimarener breed 

  10. PRION DZ- is specifically found in the brain stem, specifically the OBEX
  11. Lysosomal storage Dz-
    a specific lysosomal enzyme is defective for other reasons inoperative and as a consequence its individual substrate accumulates
  12. Laminar Cortical Necrosis is seen in…
    • Thiamin depletion/deficiency in ruminants/cats
    • SALT poisoning in cattle
  13. Focal Malacia:
    Focal symmetrical encephalomalacia in sheep (clostridium perfringens Type D entertoxemia)
  14. Haemophilis infection TME (check notes I think he changed the words but anyway) : microscopically the basic characteristic lesion is ____ and _____ in the brain as well as other organs
    • THROMBOSIS
    • SEPTIC INFARCTION
  15. ____occurs mainly in adult ruminants; microscopically it is well defined
    Listeria encephalitis
  16. Target for Listeria lesions:
    • Medulla
    • Pons
  17. _____ =>Microabscesses may occur but they are most common in sheep
    Listeria
  18. Hallmark of a viral infection in the brain is:
    • Degenerative necrosis
    • Perivascular cuffing with mononuclear cells
 (NOT neutrophils, those are indicative of bacterial infections)
    • Gliosis
  19. Canine distemper =>
    Demylination
  20. Most Common fungal infection of the CNS:
    Cryptococossis
  21. Disease Present at birth, but C/S show up at 6 months:
    Copper Dificiency
  22. Cu Deficiency => Degeneration of..
    White Matter
  23. Pathogenesis of Hydocephalus:
    • Increased Production
    • Obstruction of Flow
    • Defective Absorption
  24. Syringomyelia in ___matter of Lumbar segments
    GRAY
  25. Agg w/ degeneration of white matter:
    Astrogliosis
  26. Route for CNS infection
    Hematogenous
  27. Epsilon toxin=
    Clostridium Perfringes Type D => Enterotoxemia
  28. Symmetrical Hopping Gate=
    Syringomyelia
  29. Negri bodies in purkinji warm blooded mammals moves ____ to CNS and ____ from CNS
    • antipedially
    • centrifugally
  30. Plant Poisons: the Pallidus and substantia are specifically affected with the____
    YELLOW STAR THISTLE POISON
  31. Positive ID for Laminar Necrosis:
    Flouresence
  32. BSE involves:
    • Whole Head
    • Brain Stem
  33. Prion Gold Standard:
    Immuno-Chemistry
  34. LEAD POISONING: in subacute or chronic cases ____ may be observed in ___ matter
    • laminar cerebral cortical necrosis
    • Grey
  35. Selinium targets ___ matter
    Grey
  36. Bilateral poliomalacia=
    Lead
  37. Moldy Corn causes ____ matter necrosis, AKA
    • White
    • Leukoencephelomalacia
  38. Toxic amounts of selenium in pig rations cause …
    • Acute paralytic syndrom
    • Bilateral poliomyelomacia
  39. Salt Poisoning=>
    Necrosis of Grey matter of cerebral cortex
  40. Lesions of a parasitic Dz:
    • Hemorrhage
    • Malacia
    • Migratory Tracts
    • SOL
    • NOT DEMYELINATION OR ENCEPHELOMYELITIS
  41. Contusion- in ____ injuries,
    DIFFUSE
  42. Most common hemorrhages occur on the surface of the brain…
    OPPOSITE to the point of impact
  43. Contre Coup, 3 characteristics
    • Shearing forces exerted on the blood vessels
    • Result od the sudden movement of the brain OPPOSITE TO THE POINT OF IMPACT
    • Direct or rotational displacement of the brain over bony prominences
  44. Which is false in terms of injury to spinal cord do to intervertebral disc abnormalities?
    injury to the spine one of the most common cause of osseous malacia in dogs
  45. Degenerative lesion of the Choroid plexus (NOT A TRUE-NEOPLASM)
    Cholesteatosis
  46. ____ is well circumscribed grossly and in in association with the DURA
    Meningioma
  47. ___tumors are most often found in brachycephalic breeds
    Glial
  48. Astrocytoma VS Oligocytoma
    • Astrocytoma= Solid & color of normal tissue
    • Oligodendroglioma= soft
  49. True Rossettes form with:
    Embryonal Tumors

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