STEP 2 Rapid Review Drug Side Effects

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  1. Side effects: ACEIs
    Cough, rash, proteinuria, angioedema, taste changes, teratogenic effects
  2. Side effects: Amantadine
    Ataxia, livedo reticularis
  3. Side effects: Aminoglycosides
    Ototoxicity, nephrotoxicity (ATN)
  4. Side effects: Amiodarone
    • Acute: AV block, hypotension, bradycardia
    • Chronic: pulm fibrosis, peripheral deposition leading to bluish discoloration, arrhythmias, hypo/hypertyroidism, corneal deposition
  5. Side effects: Amphotericin
    Fever/rigors, nephrotox, bone marrow suppression, anemia
  6. Side effects: Antipsychotics
    Sedation, acute dystonic reaction, akathisia, parkinsonism, tardive dyskinesia, NMS
  7. Side effects: Azoles
    Inhibition of P450 enzymes
  8. Side effects: AZT
    Thrombocytopenia, megaloblastic anemia
  9. Side effects: B-blockers
    Asthma exacerbation, masking of hypoglycemia, impotence, bradycardia, AV block, CHF
  10. Side effects: Benzodiazepines
    Sedation, dependence, respiratory depression
  11. Side effects: Bile acid resins
    GI upset, malabsorption of vitamins/medications
  12. Side effects: CCBs
    Peripheral edema, constipation, cardiac depression
  13. Side effects: Carbamazepine
    Induction of P450, agranulocytosis, aplastic anemia, liver toxicity
  14. Side effects: Chloramphenicol
    Gray baby syndrome, aplastic anemia
  15. Side effects: Cisplatin
    Nephrotoxicity, acoustic nerve damage
  16. Side effects: Clonidine
    Dry mouth; severe rebound headache and hypertension
  17. Side effects: Clozapine
  18. Side effects: Corticosteroids
    Mania, hyperglycemia, immunosuppression, bone mineral loss, thinning of skin, easy bruising, myopathy, cataracts (chronic)
  19. Side effects: Cyclophosphamide
    Myelosuppression, hemorrhagic cystitis
  20. Side effects: Digoxin
    GI disturbance, yellow visual changes, arrhythmias (junctional tachycardia or SVT)
  21. Side effects: Doxorubicin
    Cardiotoxicity (cardiomyopathy)
  22. Side effects: Ethyl alcohol
    Renal dysfunction, CNS depression
  23. Side effects: Fluoroquinolones
    Cartilage damage in children; Achilles tendon rupture in adults
  24. Side effects: Furosemide
    Ototoxicity, hypokalemia, nephritis, gout
  25. Side effects: Gemifibrozil
    Myositis, reversible increase in LFTs
  26. Side effects: Halothane
    Hepatotoxicity, malignant hyperthermia
  27. Side effects: HCTZ
    Hypokalemia, hyponatremia, hyperuricemia, hyperglycemia, hypercalemia
  28. Side effects: HMG-CoA reductase inhibitors (statins)
    Myositis, reversible increase in LFTs
  29. Side effects: Hydralazine
    Drug-induced SLE
  30. Side effects: Hydroxychloroquine
  31. Side effects: INH
    Peripheral neuropathy (prevent with pyridoxine/Vit B6), hepatotoxicity, inhibition of P450, seizures with overdose, hemolysis in G6PD
  32. Side effects: MAOIs
    Hypertensive tyramine reaction, serotonin syndrome (with meperidine)
  33. Side effects: Methanol
  34. Side effects: Methotrexate
    Hepatic fibrosis, pneumonitis, anemia
  35. Side effects: Methyldopa
    + Coombs test, drug-induced SLE
  36. Side effects: Metronidazole
    Disulfiram reaction, vestibular dysfunction, metallic taste
  37. Side effects: Niacin
    Cutaneous flushing
  38. Side effects: Nitroglycerin
    Hypotension, tachycardia, headache, tolerance
  39. Side effects: Penicillamine
    Drug induced SLE
  40. Side effects: Penicillin/B-lactams
    Hypersensitivity reactions
  41. Side effects: Phenytoin
    Nystagmus, diplopia, ataxia, arrhythmia (in toxic doses) gingial hyperplasia, hirsutism, teratogenic effects
  42. Side effects: Prazosin
    First-dose hypotension
  43. Side effects: Procainamide
    Drug-induced SLE
  44. Side effects: Propylthiouracil
    Agranulocytosis, aplastic anemia
  45. Side effects: Quinidine
    Cinchonism (headache, tinnitus) thrombocytopenia, arrythmias (e.g. torsades de pointes)
  46. Side effects: Reserpine
  47. Side effects: Rifampin
    Induction of P-450 enzymes; orange-red body secretions
  48. Side effects: Salicylates
    Fever; hyperventilation with respiratory alkalosis and metabolic acidosis; dehydration, diaphoresis, hemorrhagic gastritis
  49. Side effects: SSRIs
    Anxiety, sexual dysfunction, serotonin syndrome if taken with MAOIs
  50. Side effects: Succinylcholine
    Malignant hyperthermia, hyperkalemia
  51. Side effects: TCAs
    Sedation, coma, anticholinergic effects, seizures, and arrythmias
  52. Side effects: Tetracyclines
    Tooth discoloration, photosensitivity, Fanconi's syndrome, GI distress
  53. Side effects: Trimethoprim
    Megolblastic anemia, leukopenia, granulocytopenia
  54. Side effects: Valproic acid
    Teratogenicity leads to neural tube defects; rare fatal hepatotoxicity
  55. Side effects: Vancomycin
    Nephrotoxicity, ototoxicity, "red man syndrome" (histamine release; not an allergy)
  56. Side effects: Vinblastine
    Severe myelosuppression
  57. Side effects: Vincristine
    Peripheral neuropathy, paralytic ileus
Card Set:
STEP 2 Rapid Review Drug Side Effects
2012-05-04 16:14:06

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