airway drugs

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  1. Theophylline MOA
    • Class: Xanthine Derivative
    • MOA: increases levels of cAMP which causes bronchodilator
  2. Theophylline uses
    • Asthma
    • Chronic bronchitis
    • emphysema
  3. Theophylline contras
    • allergy
    • uncontrolled dysrhythmias
    • seizures
    • hyperthyroidism
    • peptic ulcers
  4. Theophylline SE
    • N/V/D, reflux, sinus tachycardia, palpitations,
    • ventricular dysrhythmias
  5. Theophylline
    • Increases urine output
    • Increases BG
    • Maintain therapeutic range (10-20)
    • Limit caffeine
    • Watch BUN and CREATINE
    • Decreased effectiveness with smoking, low carbs, high protein, and charcoal meats
    • Take at same time to maintain therapeutic range
    • Antidote= activated charcoal
  6. Aminophylline
    • Injectable theophylline- used by IV with
    • asthmatics who do not respond to others
  7. Ipratropium (Atrovent)
    • Class: Anitcholinergic
    • MOA: block acetylcholine receptor, dilates blood vessels
  8. Ipratropium (Atrovent) uses
    longer term prevention of vasospasm
  9. Ipratropium (Atrovent) contras
    drug, peanut, soybean, and legume allergy
  10. Ipratropium (Atrovent) SE
    • “can’t see, pee, spit, s**t”, increase IOP, HA,
    • cough, anxiety
  11. Ipratropium (Atrovent) Imps
    • Not alone in acute attacks (available in duoneb)
    • Increase fluids
    • MDI administration
    • Rinse mouth after
    • Assess for Allergies, palpitations, BPH, Glaucoma
  12. montelukast (Singulair)
    • Class: leukotriene receptor antagonist (block D4)
    • MOA: prevent contraction of smooth muscle, decrease secretions, decrease vascular permeability
  13. montelukast (Singulair) uses
    prevention and long term treatment of asthma
  14. montelukast (Singulair) contras
    allergy to lactose, titanium, cellulose derivatives
  15. montelukast (Singulair) SE
    HA, dyspepsia, nausea, dizzy, insomnia
  16. montelukast (Singulair) imps
    • Increase fluids
    • Watch ALT/AST
  17. Albuterol (proventil)
    • Class: beta2 agonist
    • MOA: stimulate beta2 receptors, dilates blood vessels
  18. Albuterol (proventil) uses
    • asthma
    • bronchitis
  19. Albuterol (proventil) contras
    • allergy, uncontrolled dysrhythmias, high risk of
    • stroke
  20. Albuterol (proventil) SE
    insomnia, restless, cardiac stimulation, anorexia, hyperglycemia, tremors, vascular HA
  21. Albuterol (proventil) Labs
    potassium, glucose level
  22. Albuterol (proventil) imps
    • Check fluorocarbon propellant allergy
    • Check caffeine use
    • Teach MDI use
    • Increase fluids
    • Practice good health habits
  23. fluticasone (Flovent)
    • Class: corticosteroid
    • MOA: reduce inflammation; enhance beta agonists
  24. fluticasone (Flovent) uses
    long term control of persistent bronchial asthma
  25. fluticasone (Flovent) contra
    fungal infections
  26. fluticasone (Flovent) SE
    irritation, coughing, dry mouth, oral fungus
  27. fluticasone (Flovent) imps
    • Take steroid inhaler 2-5 min after bronchodilator
    • Rinse mouth after
    • Increase fluids
    • Teach that it is long term tx, not for use in acute situations
  28. Advair
    • Salmetrol (long acting(12 hr) beta2 agonist and fluticasone
    • Used: COPD and asthma
  29. Advair imps
    • Take steroid inhaler 2-5 min after bronchodilator
    • Rinse mouth after
    • Increase fluids
    • Teach that it is long term tx, not for use in acute situations
  30. Epinephrine
    • Class: nonspecific alpha/beta agonist
    • MOA: constricts blood vessels, decreasing edema, swelling, and secretions
  31. Epinephrine uses
    relief of bronchospasm
  32. Epinephrine SE
    insomnia, restless, anorexia, cardiac stimulation, hyperglycemia, tremor, vascular HA
  33. Epinephrine Labs
  34. Epinephrine imps
    • Limit caffeine use
    • Monitor VS
    • Report new symptoms
  35. MDI procedure
    • Shake
    • Tilt head back slightly
    • Open mouth
    • 1-2 finger widths from mouth
    • Exhale, press, and breath in
    • Hold for at least 10 seconds
    • Exhale
    • Rinse mouth
  36. MDI imps
    • Teach use
    • Wait 1-2 min between puffs
    • Wait 2-5 min between meds
    • Rinse mouth after
Card Set:
airway drugs
2012-05-06 14:00:56
pharm test

broncho dilators and others
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