Nursing interventions for Pioglitazone (Actose)?
Emphasize the need for liver function tests as recommended. Instruct patients to report symptoms of unexplained nausea, vomiting, abdominal pain, fatigue, anorexia, or dark urine.
RATIONALE: Rare cases of liver failure have occurred with pioglitazone. Liver function tests are measured at the start of therapy and at regular intervals thereafter. Not recommended for moderate to severe liver impairment or in patients with jaundice.
Advise women of the need for effective contraception during therapy.
RATIONALE: Administration of pioglitazone with certain oral contraceptives may reduce the plasma concentration of the oral contraceptive. Post-menopausal women with insulin resistance may resume ovulation during therapy.
Monitor weight; assess for edema and shortness of breath.
RATIONALE: Fluid retention can lead to weight gain and can cause or exacerbate congestive heart failure.