Gyn Onc

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Author:
shosh114
ID:
153269
Filename:
Gyn Onc
Updated:
2012-05-10 06:51:45
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OB II
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Description:
OB II
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  1. What is the most common benign gynecological tumor?
    • Uterine fibroids
    • SM tumor
    • Seen in 40-50% of reproductive age women
    • Tend to regress after menopause
  2. Which type of uterine leiomyoma is most likely to be symptomatic?
    Submucosal--can cause bleeding and infertility
  3. 4 approaches to management of uterine fibriods
    • 1. Watchful waiting--asymptomatic, fibroids under 8 cm, not submucosal
    • 2. Medical--antiprostaglandins or tranexamic acid
    • 3. Interventional radiology--embolize uterine artery, shrinks fibroid and decreases bleeding
    • 4. Surgical--myomectomy preserves fertility, hysterectomy can be used for giant fibroids
  4. Most common gyne cancer in North America?
    Uterine (cervical is more common in some low socioeconomic areas)
  5. Risk factors for endometrial cancer
    • 1. Unopposed estrogen (PCOS, obesity, HRT)
    • 2. Nulliparity
    • 3. Late menopause
    • 4. Tamoxifen
    • 5. Estrogen-producing ovarian tumor (e.g. granulosa cell)
    • 6. HNPCC
  6. Categories of endometrial cancer
    • 1. Adenocarcinoma (80%)
    • 2. Adenosquamous (15%)
    • 3. Papillary serious adenocarcinoma (4%)
  7. Most common clinical presentation in endometrial cancer
    Post-menopausal bleeding
  8. Stage I endometrial cancer
    Confined to uterine corpus
  9. Stage II endometrial cancer
    Involves corpus and cervix
  10. Stage III endometrial cancer
    Invades beyond uterus but is confined to pelvis
  11. Stage IV endometrial cancer
    Mets outside of pelvis
  12. Most common site of distant mets for endometrial cancer
    Lungs
  13. Uterine sarcoma
    Rare uterine tumor of stromal origin. 5 year survival is 35%.
  14. Typical presentation of leiomyosarcoma
    Rapidly enlarging uterus
  15. US characteristics of malignant ovarian tumors
    • 1. Over 10 cm
    • 2. Bilateral
    • 3. Cystic and solid elements
    • 4. Multiloculated
    • 5. Thick septae
    • 6. Ascites
  16. Most common solid ovarian neoplasm
    • Benign cystic teratoma (dermoid tumor)
    • 20% bilateral
    • Increased risk of ovarian torsion
  17. What does a dysgerminoma produce?
    Lactate dehydrogenase
  18. Most common malignant ovarian tumor
    • Serous adenocarcinoma
    • Contains psammoma bodies
  19. What ovarian tumor may be complicated by pseudomyxoma peritonei?
    Mucinous adenocarcinoma
  20. Ovarian stromal tumors
    • Benign ovarian fibroid
    • Granulosa/theca cell tumor
  21. Tumor that metastasizes from the GI tract to the ovaries
    • Krukenberg tumor
    • Signet ring cells
  22. Triad associated with Meig's syndrome
    • Ovarian fibromas
    • Ascites
    • Right pleural effusion
  23. Causes of elevated CA-125
    • Benign
    • Benign ovarian neoplasm
    • Endometriosis
    • Pregnancy
    • Fibroids
    • PID
    • Cirrhosis
    • Pancreatitis
    • Renal failure
    • Malignant
    • Tumors of the ovary, uterus, pancreas, stomach, colon, or rectum
  24. Stage I ovarian cancer
    Tumor limited to ovaries
  25. Stage II ovarian cancer
    Tumor involves one or both ovaries with extension into the pelvis
  26. Stage III ovarian cancer
    Peritoneal implants

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