Patho & Pharmo wk 7 Diabetes

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  1. What was the name of the disorder that was known
    to produce large amounts of honey sweet urine?
    Diabetes Mellitus
  2. When was Insulin discovered?
  3. Why were there complications in the early days?
    Infrequent doses, Animal insulin differs from human
  4. What hormonal action does Insulin do?
    Lowers blood sugar levels, it does this by moving the glucose from the blood stream into the cells.
  5. Which type of diabetes destroys the Islets of Langerhans in the pancreas, which leads to the absence of insulin production?
    Type 1, the patient still absorbs glucose from the GIT into the blood stream but it can’t move into the cells. BSL rises with glucose spilling into the urinary filtrate.
  6. Why would a diabetic patient experience thirst?
    Glucose has a strong osmotic pull. The patient loses excess fluid from the blood stream as urine and the patient becomes dehydrated hence the thirst. To quench the thirst the patient drinks large volumes of water to compensate.
  7. Which is the correct name for excessive gluttonous eating?
    • A. Polyuria
    • B. Polydipsia
    • C. Polyphagia
    • D. Polyploid
  8. Which form of diabetes is insulin resistant?
    Type 2, the cell membrane is resistance to Insulin. Treatment involves dietary reduction, exercise and medication to improve cell response to insulin.
  9. What is Neuropathy?
    Inflammation or degeneration of the peripheral nerves
  10. Describe the difference between Micro and Macro Vascular?
    • Micro-vascular refers to the portion of the circulatory
    • system that is comprised of capillaries, such as eyes or kidneys. Macro refers to the arties section dues to accelerated AS diabetes carries increased ischaemic heart disease.
  11. Why would a diabetic patient suffer sensory loss including motor function?
    Due to thickening and sclerosing of nutrient arterioles and capillaries that supply the damaged nerve.
  12. What else does Insulin do other than regulation of sugar levels?
    It transports amino acids into the cells. Regulates the amount of fats stored and it usage.
  13. What two roles does the pancreas have on the body?
    The endocrine and exocrine system
  14. What organ does not require Insulin to function?
    The Brain
  15. What are the 3 actions of Sulponylurea drugs?
    Promote insulin release, slowing down the output from the liver and boosting of the insulin receptors
  16. Which diabetic state is insulin lacking?
  17. Name an adverse effect of Metformin?
    Tolerance, build up of Lactic acid and also a shift in PH balance
  18. Which drugs would you use if the patient were borderline
    Hyper or Hypoglycaemic?
  19. What is the function of Acarbose?
    It is a complex polysaccharide that competes in the gut for binding site for sugar absorption with di & mono saccharides therefore lowering the GI.
  20. What is Insulin measured in and why?
    Units; it is defined by the level of activity. Such as the metabolic status, height and weight. 100 units per ml.
  21. Is Insulin and agonist or antagonist in corticosteroid therapies?
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Patho & Pharmo wk 7 Diabetes
2012-06-01 06:01:42

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