Gram positive bacteria

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Author:
dtminhthu
ID:
15342
Filename:
Gram positive bacteria
Updated:
2010-04-20 10:29:55
Tags:
gram positive bacteria microbiology
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Description:
Gram positive bacteria, microbiology
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  1. Spore forming, Gas Gangrene/ Myonecrosis (mediated by alpha toxin), foul-sweet odor to skin discharge, renal failure, hypotension, shock
    Clostridium perfringens
  2. Endospores, Alpha toxin (PLC, hepatic toxicity, lyses RBCs, WBCs, endothelial cells, myocardial dysfxn), encapsulation
    Clostridium perfringens
  3. Endospores, Alpha toxin (PLC, hepatic toxicity, lyses RBCs, WBCs, endothelial cells, myocardial dysfxn), encapsulation. what's the O2 requirement?
    Anaerobic
  4. Spore forming, Gas Gangrene/ Myonecrosis (mediated by alpha toxin), foul-sweet odor to skin discharge, renal failure, hypotension, shock. What's the shape and where are they found?
    Rods. soil, H2O, sewage microbial flora in GI
  5. Tetanospasmin retrograde transport to CNS, generalized (most common) & localized tetanus, spore forming
    Clostridium tetani
  6. Tetanospasmin: plasmid-encoded, heat-labile neurotoxin (A-B toxin), motility
    Clostridium tetani
  7. Anaerobic, non-polar flagella, bacillus bacteria prone to O2 toxicity. Patient experiences jawlock spasm.
    Clostridium tetani
  8. foodborne or transmitted via traumatic implant. Has toxin as virulence factor, anaerobic, non-polar flagella, bacillus. Causes flaccid paralysis
    Clostridium botulinum.
  9. Antibiotic resistance, enterotoxin A (Damages mucosa leading to fluid increase & granulocyte attractant), cytotoxin B (damages mucosa). Gains foothold when normal gut bacterial flora is disrupted.
    Clostridium difficile

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