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1st line for gonorrhea
Tx for listeria monocytogenes in infants
-alternate for bacterial meningitis in pts allergic to cephalosporins/penicillins
-Rickettsial infections in pregnancy/young children
-Lymes disease from borrelia burgdorferi (DOC)
Tetracyclines (use erythromycin in pregnant pts)
-mycoplasma pneumonia (ESP in pregnant pts) (DOC)
-chlamydial infections in pregnant patients (DOC)
Mycobacterium avium (in AIDS pts)
single dose to treat uncomplicated genital chlamydial
Azithromycin - does not inhibit CYP p450s
Gentamicin-resistant bacterial endocarditis
Gentamicin is an option for treating ______.
Pseudomonas aeruginosa infection in cystic fibrosis
serious noscomial infections → broad spectrum
ulcerative colitis → 5-aminosalicylate is active agent
prevention of infections in pts with 2nd/3rd degree
-uncomplicated UTIs → DOC for empirical UTI
-Pneumocystis jiroveci pneumonia in AIDS pts (also
could use pentamidine for this)
Pseudomonas, prostatitis, bacterial diarrhea
strep pneumoniae, CAP
strep pneumoniae, anaerobes, CAP
Moxifloxacin- eliminated via non-renal mechanisms
ONLY used to treat chronic UTIs
-good penetration into abscesses (anarobes - B.
Fragilis, clostridium perfringens)
-causes superinfection of clostridium difficile
-MRSA, diarrhea caused by C. diff.
topically applied for skin infections
-anaerobes, clindamycin-resistant B fragilis...DOC for
B. fragilis in adults!!
-pseudomembranous colitis caused by C. Diff!!! (DOC)
ophthalmic and dermatologic ointments - eye infections,
-life threatening infections
-Enteroccoccus FAECIUM (but NOT faecalis)
complicated skin infections (depolarizes cell membranes,
SEs: myopathy, peripheral neuropathy)
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