DA3

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Author:
HUSOP2014
ID:
153899
Filename:
DA3
Updated:
2012-05-15 00:01:56
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Husop DA3 Drugs
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Description:
Devaud lectures: class listed drugs
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  1. Benzothiadiazines
    • Hydrochlorothiazide
    • Chlothialidone
    • SE: hypokalemia, ED, Gout, tachycardia or cardiac death (loss of K+), increased LDL, cholesterol, glucose tolerance
  2. Loop diuretics
    • Furosemide- good for edema
    • Amiloride- K sparing
  3. B-adrenergic R antagonist
    ADR: Asthma, Kiabetes, SA or AV nodal dysfunction, lipid changes, rebound hypertension
  4. Alpha1- adrenergic R antagonists
    • Prazosin
    • Terazosin
    • Doxazosin
    • SE: NaCl and water retention
  5. Mixed Alpha/Beta R antagonist
    • Labetalol
    • Carvedilol
  6. NE substitute for Hypertension
    • Methyldopa- metabolite active
    • SE: Sedation, Depression, Dry mouth, Parkinsonian like symptoms, hepatotoxicity
  7. Alpha-2 Agonist
    • Clonidine
    • Guanabenz
    • Guanfacine
    • SE: seation, xerostomia, ED, HypoT, Nightmares
  8. Vesicular catecholamine transporter (VMAT2)
    Reserpine- prevents storing NE and DA
  9. Dihydropyridines (for HT)
    • Ca++ channel Antagonists
    • Amlodipine
    • Nifedipine
    • Verapamil
    • SE: peripheral edema, GERD,
  10. Cholinergic Agonists
    • Bethanechol
    • Methacholine
    • Carbochol
    • Pilocarpine
    • Cevimeline
    • Muscarine, Arecolin
  11. Cholinergic Antagonists
    • Atropine and Scopolamine
    • Pirenzepine and telensepine
    • ipratropium and tiotropium
    • Propatheline and oxybutynin
    • Benztropine mesylate, tropicamide, diclyclomine,
    • Darifenacin, Solifenacin, Fesoterodine
  12. Acetylcholinesterase Inhibitors
    • Neostigmine, physostigmine, pyridostigmine (MG)
    • Donepezil, Galantamine, Rivastigmine (Alzheimer's)
    • Diisopropyl flurophosphate, isoflurophate, ecothiophate (glaucoma)
  13. Nicotinic Agonists
    • Nicotine
    • Varenicline
    • Lobeline
  14. Neuromuscular Blocking Agents
    • Curare, Pancuronium (competative inhibitors)
    • tubocurarine, Mivacurium, atracurium, Rocuronium, Gallamine (competitive paralytics)
    • Decamethonium (agonist)
    • Succinylcholine (depolarizing paralytics)
    • Botulinum Toxin (Ach release inhibitor)"Botox"
  15. Alpha-1 Agonist
    • Phenylephrine
    • Mephenterimine
    • Metaraminol
    • Midodrine
  16. Alpha-2 Agonists
    • Clonidine
    • Apraclonidine
    • Guanfacine and Guanabenz
    • Methyldopa
    • Tizanidine
  17. Non-Selective Alpha Agonists
    • Pseudoephredrine
    • Propylhexedrine
    • xylometazoline
    • oxymetazoline
    • Naphazoline
  18. Non-Selective Adrenergic Agonists
    • Epinephrine
    • Ephedrine
    • Dopamine
  19. Alpha-1 Antagonists
    • Prazosin
    • Terazosin
    • Doxazosin
    • Indoramin
    • Tamsulosin, Alfuzosin, Silodosin
  20. Alpha-2 Antagonist
    Yohimbine
  21. Non-Selective Alpha Antagonist
    • Phentolamine
    • Phenoxybenzamine
  22. Beta-1 Antagonist
    • Metoprolol
    • Atenolol
    • Esmolol
    • Acebutolol
  23. Non-Selective Beta Antagonists
    • Propranolol
    • Naldolol
    • Timolol
    • Pindolol
    • Labetolol
  24. Mixed Action Beta Antagonists
    • Carvedilol
    • Carteolol
    • Betaxolol
    • Celiprolol
  25. Monoamine Oxidase Inhibitors
    • Iproniazid (A)
    • Tranylcypromine (A)
    • Moclobemide (A)
    • Selegiline (B)
  26. Catechol-O-methyl Transferase (COMT)
    • Entacopone
    • Tolcapone
  27. Catecholamine Uptake Inhibitors/Releaser
    • Cocaine- uptake inhibitor
    • Ampehtamine, Dextro, Metha- enhance release
    • Methylphenidate- enhance release
    • Modafinil, Atomexatine-enhance release
    • Reserpine- blocks uptake/storage to deplete Epi, NE
  28. Tricyclic Anti-depressants
    • Amitriptyline (5HT)
    • Clomiramine (5 HT)
    • Desipramine (5HT, DA)
    • Nortryptyline (NE)
  29. SSRI
    • Citalopram
    • Escitalopram
    • Fluoxetine
    • Paroxetine
    • Sertraline
  30. SNRI
    • Venlafaxine
    • Duloxetine
  31. Atypical Anti-Depressants
    • Buproprion (5HT, DA)
    • Mirtazapine (A2 Antagonis)
    • Trazodone (5HT)
  32. Mood Stabilizers-Anti-convulsants
    • Lithium (DA-synthesis inhibition)
    • Darbamazepine, Oxcarbazepine (VG-Na-channels)
    • Lamotrigine (I- glutamate release0
    • Valproic Acid (increase GABA)
    • Quetiapine (DA1,2, 5HT1,2)
    • Aripiprazole (D23, 5HT1a,2a)
    • Olanzepin (2nd gen thienobenzodiazepine)
  33. H-1 antagonists (Anti-Emetics)
    • Meclizine
    • Cyclizine
    • Diphenhydramine
    • Promethazine
  34. D2 Antagonists (Anti-Emetics)
    • Promethazine
    • Prochlorperazine
    • Chlorpromazine
    • Metoclopramide
    • Haloperidol
    • Droperidol
  35. 5-HT3 Antagonists (Anti-Emetics)
    • Ondansetron
    • Granisetron
    • Dolasetron
    • Palonosetron
  36. CB-1 Agonist (Anti-Emetics)
    Dronabinol
  37. Benzodiazepines (Anti-Emetics)
    • Diazepam
    • Lorazepam
  38. Benzodiazepines (Sedative Hypnotics)
    • Diazepam, Alprazolam, Flurazepam, Quazepam
    • Temazepam and Triazolam (insomnia)
    • Zolpidem, Zaleplon, Eszopiclone ( benzo-like, short acting)
  39. Benzodiazepine Antagonist
    Flumazenil

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