Epinephrine is a naturally occuring catecholamine that increases heart rate, cardiac contractile force, myocardial electrical activity, systemic vascular resistance and systolic blood pressure, and decreases overall airway resistanse and automaticity. It also, through bronchial artery constriction, may reduce pulmonary congestion and increase tidal volume and tidal capacity.
Asthma/COPD, to restore rhythm in cardiac arrest, and severe allergic reactions.
Narrow angle glaucoma, traumatic, hemorrhagic, and cardiac shock.
- - Dosage/Route:
- Arrest: 1 mg of 1:10,000 IV/3 to 5 mins (ET 2 to 2.5 mg of 1:1,000)
- Pedi: 0.01 mg/kg 1:10,000 IV/IO (ET: 0.1 mg/kg 1:1,000). All subsequent doses 0.1 mg/kg IV/IO. No max.
- Adult Bradycardia: 2-5 mcg/min IV drip
- Allergic reactions: 0.3 to 0.5 mg of 1:1,000 subcutaneously/5 to 15 min as needed or 0.5 to 1 mg of 1:10,000 IV if subcutaneous dose ineffective or severe reaction
- Pedi: 0.01 mg/kg (Max 0.5) of 1:1,000 SQ/10 to 15 min or 0.01 mg/kg of 1:10,000 IV if subcutaneous dose ineffective or severe.
- Asthma/COPD 0.3mg 1-1,000 SQ