chapter 20, hepatitis

Home > Flashcards > Print Preview

The flashcards below were created by user tville01 on FreezingBlue Flashcards. What would you like to do?

  1. inflammation of liver
    viral hepatitis
  2. how do the cells damage the liver in hepatitis
    • direct from virus
    • cell mediated response to virus
  3. what happens after cell injury occurs in the liver
    • inflammation and necrosis
    • biliary stasis develops
    • bile backs up into blood
    • hepatocytes regenerate, or form fibrious scar tissue(obstructs blood vessels or bile ducts)
  4. what causes Hep A
    RNA virus
  5. how is Hep A transmitted
    • feces
    • fecal-oral
    • sexual transmission(not STD)
    • Highly contagious
    • common in underdeveloped countries
  6. least serious form of hepatitis
  7. what is the incubation period for Hep A
    2-6 Weeks
  8. when is Hep A most contagious
    10-14 days before symptoms during fecal shedding
  9. what causes Hep B
    DNA double strand virus
  10. which Hepititis is species specific to humans and primates
    Hep B(serum hep)
  11. what is the whole viron for Hep B refered to as
    dane particle
  12. Describe the virus that causes Hep B
    • 2 core antigens(HBcAg & HBeAg)
    • 1 surface antigen(HBsAg/australia antigen)
  13. how is Hep B transmitted
    • percutaneous and premucosal exposure to body fluid
    • STD
    • Fomites
    • unsanitary conditions
  14. how long can the Hep B virus survive on enviormental surfaces
    7 days
  15. Who is at risk for Hep B
    • health care workers
    • IV drug users
    • homosexuals
    • infants of infected moms
    • dialysis patients
  16. what is the incubation period for Hep B
    2-6 months
  17. all people with what surface antigen(produced in excess by hepatocytes) are potentially infectious for Hep B
    HBsAg/australian antigen
  18. how soon after exposure can HBsAg appear
    2 weeks
  19. What causes Hep C
    double stranded RNA virus
  20. describe the virus that causes Hep C
    • 6 genotypes
    • over 50subtypes
    • 20% of viral hep
    • genotype 1 common in US
  21. Which age group is more likely to get Hep C
  22. how is Hep C transmitted
    • blood and body fluids
    • infants of infected mothers
    • parenteral route(sharing needles)
    • dialysis patients
    • sex
  23. how severe is Hep C
  24. what is the incubation period of Hep C
    • 2weeks- 6 months
    • 6-9 weeks average
  25. what are the stages of Hepatitis
    • preicteric
    • icteric
    • posticteric
  26. What are the signs and symptoms during the preicteric stage(prodromal) of Hepatitis
    • fatigue& maliase
    • anorexia, nausea& vomiting
    • changes in smell & taste
    • elevated liver enzymes
  27. what causes liver enzymes to be elevated
    released from necrotic hepatocytes
  28. What are the signs and symptoms of the icteric stage of Hepatitis
    • bilirubin increases causing;
    • jaundice
    • clay stools
    • dark urine
    • hepatomegaly
  29. in which Hepatitis is the icteric stage longest
    Hep B
  30. What happens during the posticteric stage of Hepatitis
  31. what diagnostic test are used for Hepatitis
    • H&P
    • urinalysis for bilirubin
    • serum levels of liver enzymes
    • bilirubin serum levels
  32. what are the serum markers for Hep A
    • anti-HAV IgM
    • anti-HAV IgG
  33. in Hep A which antibodiy in the blood indicates lifetime immunity
    anti-HAV IgG
  34. what are the serum markers for Hep B
    HBsAg/australian antigen
  35. If you recover from Hep B will you have surface antigens
    only if you are a chronic carrier and infectious
  36. what are the serum markers for Hep C
    anti-HCV, RNA, PCR(polymerse chain reaction)
  37. what are complications of Hep A
    • never goes to chronic Hep or cirrhosis
    • fuliminating form causing hepatic failure rare
    • never carriers
  38. what are the complications of Hep B
    • carrier state
    • fulminant hepatitis=liver failure=25-90% mortality
    • asymptomatic
  39. what are the complication of Hep C
    • Cirrhosis5-20 deaths out of 100
    • chronic infection=1-5 deaths out of 100
    • chronic liver disease= 60-70 out of 100
    • carrier
  40. In which cases of Hepatitis can chronic active Hepatitis occur
    B & C, progresses to cirrhosis
  41. what types of Hepatitis can develop liver cell carcinoma
    • B & C
    • rare, late complication
  42. what is the treatment for Hepatitis
    • pallative
    • no specific treatment
    • alpha interferon for chronic Hep B & C
    • liver transplants
  43. what are preventative measures for Hepatitis
    • Immunoglobulins
    • Vaccines
  44. what immunoglobulin is given to Hep A patients
    ISG/Immune Serum Globulin
  45. what immunoglobulin is given to Hep B patients
    HBIG/Hepatitis Immune Globulin
  46. which Hepatitis is not effected post-exposure prophylaxis by immunoglobulins
    Hep C
  47. Which Hepatitis has vaccines available
    A & B
  48. Who is the Hep A vaccine recommended for
  49. who is the Hep B vaccine recommended for
    health care workers
  50. what are you recieving when you get a Hep B vaccine
    • Spikes HBsAg
    • very safe
    • genetically engineered
  51. How is recombivax HB/Hepatavax B given
    • 3 IM doses
    • 0-1-6
  52. what are the prognosis for the different types of Hep
    • A=good
    • B=most recover, more severe
    • C=15-25% recover, most develop chronic HCV Infection

Card Set Information

chapter 20, hepatitis
2012-05-21 16:05:15
chapter 20 hepatitis

chapter 20, hepatitis
Show Answers:

What would you like to do?

Home > Flashcards > Print Preview