Anti-dysrhythmic/ NA+ blocker
Lidocaine is an anti-dysrhythmic that suppresses automaticity and raises stimulation threshold of the ventricles. It also causes sedation, anticonvulsant, and analgesic effects.
Pulseless ventricular tachycardia, ventricular fibrillation, ventricular tachycardia (w/ pulse)
Hypersensitivity to amide-type local anesthetics, supraventricular dysrhythmias, Stokes-Adams syndrome, 2nd and 3rd degree heart blocks, and bradycardias.
Hepatic or renal impairment, CHF, hypoxia, respiratory depression, hypovolemia, myasthenia gravis, shock, elderly.
- - Dosage/Route:
- Cardiac Arrest: 1 to 1.5 mg/kg slow IV, repeated every 3 to 5 mins, up to 3 mg/kg. Follow conversion with a drip of 2 to 4 mg/min.
- Pedi: 1 mg/kg slow IV, repeated every 3 to 5 mins, up to 3 mg/kg. Follow conversion with a drip of 20 to 30 mcg/kg/min.
- Ventricular Tachycardia (w/ pulse): 1 to 1.5 mg/kg slow IV. Consider lower dose for elderly. May repeat 1/2 dose every 5 to 10 mins until conversion up to 3 mg/kg. Follow conversion with 2 to 4 mg/min.
- Pedi: 1 mg/kg followed by a drip of 20 to 50 mcg/kg/min.