Clin Med: Infectious Diseases

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  1. High Virulence
    Ability of agent to cause disease in normally resistant individual
  2. Low virulence
    Agent is only effective in host w/ low resistance
  3. Pathogenicity
    • 1- Ability to produce infection & propagate in host- overcomes host defenses
    • 2- Agents ability to generate products that cause tissue damage
    • 3- Host cellular responses to infectious agents- also leads to tissue damage (hyersensitivity reactions)
  4. Virus
    • Smallest pathogen
    • Has DNA or RNA in protein shell- capsid
    • Not capable of independent metabolsm
    • Requiring living cellsin which to replicate- may or may not interfere w/ cell functions
  5. Virus Cycle
    • Attach to cell
    • Penetrate it
    • Un-coat
    • Replicate
  6. Viremia
    Presence of viruses in the blood
  7. Influenza
    • Viral respiratory diease
    • Fever, headache, myalgia,
    • Complications: bronchitis and bacterial pneumonia
    • Influenza Virus A
    • Influenza Virus B
  8. Measles
    • Rubeola
    • Highly contagious
    • RNA measles virus
    • Incubation period: 10-21 days
    • Fever, cough, conjunctivitis, malaise
    • Rash
  9. Rubella
    • Viral RNA disease
    • Children 5-15
    • Mildly contageous
    • Lymphadenopathy, rash 3-5 days, conjuctivitis
  10. Mumps
    • Acute generalized infection, RNA virus
    • Fever, malaise, parotitis
    • Complications: meningitis, pancreatitis, orchitis
Card Set
Clin Med: Infectious Diseases
Infectious Diseases
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