Infectious Disease

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Author:
kmegk22
ID:
154927
Filename:
Infectious Disease
Updated:
2012-05-20 18:32:43
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infectious diseases
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infectious diseases
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  1. Gram positive
    • cocci: staph, (MRSA) strep, enterococci
    • rods: clodi, listeria
  2. Gram neg
    • cocci: neisseria
    • coccibacillary: ancinobacter
    • rods: enterobacter, e coli, h influ, h pylori, kebsiella, legionella, proteus, pseudomonas, salmonella
  3. atypical
    chlymydia, mycoplasma, ureaplasma
  4. candida
    • albicans, parapsilosi, listiania- use fluconaone
    • krusei, glabrata- fluconazole resistant
  5. beta lactams MOA
    inhibit cell wall synthesis
  6. PCN
    good: strep, enterococcus, trepmomen, pallidum
  7. penicillinase resistant penicillians
    • methcillin, nafcillin, oxazillin, dicloxacillin
    • adds activity against MSSA
  8. aminopenicillism - amox, amp
    listeria, enterocco faecalis, listeria
  9. amino+ b lactam
    amp/sul
    pip/tazo
    ticar/clav
    amox/clav
    • staph aureus
    • e coli
    • klebsiella,
    • anerobes
  10. first generation ceph names
    • cefazolin (ancef)
    • cephalexin (keflex)
    • cefadoxil (duricef)
  11. first gen ceph coverage
    gram pos: MSSA, step, e coli, klebsiella
  12. 2nd gen names
    • cefuxoime (ceftin)
    • ceforozil (cefzil)
    • cefaclor (ceclor)

    • cefotetan -- adds anaerobic
    • cefoxitin (mefoxin)- anaerobic (prophylaxis)
  13. 3rd gen names
    • ceftriaxone (rocephin)
    • cefpodoxime
    • cefixime (subras)
    • ceftazidime (fortaz)
  14. 3rd gen coverage
    strep pneumo, less staph auerus, gram neg
  15. ceftazidime coverage
    pseudomonas
  16. 4th gen ceph
    cefepime (maxipime)

    pseudomonas with good strep, staph
  17. ceftaroline
    • MRSA
    • pseudomonas
  18. cephs do not cover
    enterococcus
  19. carbapenems
    • imipenem (primaxin)
    • doripenem (doribax)
    • meropenem (merrem)
    • ertapenem (invanz)
  20. carbapenem coverage
    • broadL pos, neg anerobes
    • MSSA,
    • B fragalis
    • pseudomonas
    • acinobacter
  21. ertapenem coverage
    • not pseudomonas, acinobacter
    • b fragilis,
    • mssa
  22. aztreonam - monobactam
    • gram neg
    • pseudomonas
  23. vanco coverage
    • MRSA,
    • strep
    • enteroccocus
    • c diff
  24. dapto coverage
    • gram pos only
    • MRSA, VRE
  25. dapto SE
    CPK, myagias

    NOT FOR PULMONARY INFECTIONs
  26. linezolid coverage
    • VRE
    • MRSA
    • s pneumo
  27. linezolid MOA and SE
    inhibits protein synthesis

    thrombocytopenia, serotonin syndrom
  28. quinupristin/dalfoprisin (synercid) coverage
    • MRSA
    • MRSE
    • VRE- NOT FACEALIS
  29. quinupristin/dalfoprisin (synercid) se
    hyperbilirubinema, phebitis, myalgias
  30. aminiglycosides coverage
    • MSSA
    • entercocc,
    • p aerugosa
    • pnseuo
    • used in combo for gram pos synergy
  31. cipro
    • gram neg
    • pseudo
    • staph
    • mycobateria
    • not strep (cap)
  32. levo
    • strep pneumo
    • cap/hap
    • pseudo
    • aneroboes: needs metro too
  33. moxi
    • gram pos
    • no pseudo
    • good for CAP, intrabdominal
  34. macrolide MOA
    protein synthesis inhib
  35. macrolide coverage
    • strep
    • resp gram neg
    • atypicals
    • mycobacteria
  36. tetracycline coverage
    • gram neg- skin and sof tissue infections
    • MRSA
    • wierd ones
    • chlyamydia
  37. clindamyxin coverage
    • gram pos
    • anerobia, staph aureus, bone, MRSA,
  38. Bacrim coverage
    • MRSA
    • gram neg- e coli, kel
    • poor agains strep
  39. metro
    • anerobic- b fragilis
    • c diff
  40. nitrofurantion
    • UTI
    • VRE
  41. fosphamycin
    • preg- uts
    • pseudo
  42. covers staph aureus
    • amin + b lactam
    • ceftriaxone
    • cefepime
    • cipro
    • nafcillin
  43. covers strep pneumo
    • pen
    • ceftriaxone
    • ceftazidime
    • linezolid
    • levo
    • azith
  44. pseudo
    • pneumonia, UTI, osteomytitis, burns, otitis, endocarditis
    • pipercillin
    • ticarcillin
    • ceftazidime
    • cefepime
    • carbapenem
    • aztreonam
    • cipro
    • aminiglycosides
    • fosphamycin
  45. MRSA- skin
    • bactrim
    • doxy
    • mino
    • clinda
    • linezolid
    • dapto
    • tige
    • ceftaroline
    • vanco
  46. MRSA- nosocomial
    • linezolid
    • quin/dal
    • dapto
    • ceftaroline
    • televancin
    • tigecyclin
    • rifampin
  47. vre facalis
    • pen g
    • amp
    • linezolid
    • dapto
    • tiga
    • doxy
  48. vre- faceium
    • pen g
    • amp
    • linezolid
    • dapto
    • tiga
    • doxy

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