Card Set Information
What are the features of the spinal cord?
continuation of medulla through foramen magnum
31 pairs of nerves (dorsal-sensory) (ventral-motor) pass through intervertebral foramena
spinal cord ends at L2
Where is lumbar puncture/spinal tap taken from?
L3/L4 (below where spinal cord ends)
What are the key features at the end of the spinal cord?
: tapering terminal end at L2
: horse tail of spinal nerves
: extension that anchors within dural sheath
What is radiculopathy?
compression of nerve in spine (herniation, bone spur, otseoarthritis, scoliosis, diabetes)
numbness, tingling, weakness
: C3, L4, L5 (lateral disk prolapse or compression)
What are the spinal cord regions?
31 segments of vertebral level exits
: brachial plexus, cervical enlargement (C3 max motor), C5 max forelimb
: trunk, intermediolateral horn enlargement (sympathetic) T5 small spinal, gross movement
: lumbar plexus, lumbar enlargement (L5-mostly gray, lower extremeity motoneurons)
: sacral plexus (with L5), pelvic muscles, posterior lower limbs
: with S4,5 innervate skin over coccyx and anus
What is a morphogen?
molecule that diffuesed to form a concentration gradient and affects developing embryo
What is BMP?
growth factor or cytokines and metabologens induces bone & cartilage formation
orchestrate tissue architecture
Where is the spinal cord derived?
neural plate (neuroectoderm)
forms nerual tube & excludes nerual crest cells which form DRGs
: primary afferent sensory
orchestrated by morphogenic proteins, SHH, creat alar and basal plates
: dorsal sensory
: ventral motor
What are Rexed's Laminae?
organization of gray matter of spinal cord
: pain, temp, proprioception & touch
II & III
: substantia gelatinosa (same stimuli)
: motor neurons in columns
: visceral nocicption
What is the somatotopic organization of spinal white matter?
representation of the body within the CNS
sacral & lumbar enter first then thoracic & cervical
dorsal colums:carry proprioceptive info
: medial 2 dorsal column, carry info from sacral & lumbar
: throracic & cervical
: ascend on same side (cervical medial, lumbar lateral)
: somatotopically (sacral lateral, cervical medial)