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How does heparin work?
Inhibits conversion of prothrombin to thrombin
Oxalate works how?
Interferes with what chemistry tests?
Binds calcium and forms insoluble complexes
Na, K, ammonia (NH3), Li
Sodium Flouride works how?
- Binds calcium amd prevents glycolysis.
- May inhibit some enzymatic methods
Prolonged tourniquet use has what effect on chemistry values?
- Increased total protein
- Decreased K
Function of proteins
- Transportation of metabolic substances.
- Part of cell membranes.
- Part of hormones and receptors
- Componants of enzymes.
Proteins are composed of?
Nitrogen differentiates proteins by what?
Carbohydrates and Lipids
Albumin is soluble in what?
Globulins are soluble in what?
Dilute salt solutions
Protein denaturation can be caused by...
Change in temperature (Rupture weak secondary and tertiary bonds)
Changes in pH (Alter Ionic Charge)
Enzyme deficiency of phenylalanine hydrolase.
Results in accumulation of phenylalanine in the blood.
Results in accumulation of phenylpyruvic acid in the urine.
Testing includes PKU and the Guthrie test.
Enzyme deficiency of tyrosine aminotransferase.
Results in the accumulation of tyrosine.
Enzyme deficiency of homogentisic oxidase
Results in the accumulation
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