Unit 18 .txt

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Unit 18 .txt
2012-05-23 03:29:38
Pharmacology Glaucoma

Chapter 18 of the Pharmacology for Pharmacy Technicians Text by Moscou/Snipe
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  1. Aqueous Humor
    Fluid made in the front part of the eye
  2. Central Vision
    Sight straight ahead or when you read
  3. Conjunctiva
    Transparent mucous membrane that lines each lid and continues over the surface of the eyeball
  4. Cornea
    Clear part of the eye located in front of the iris
  5. Glaucoma, angle closure
    Sudden increase in intraocular pressure caused by obstruction of the drainage portal between the cornea and iris (angle) that can rapidly progress to blindness
  6. Glaucoma, open angle
    Disorder characterized by elevated pressure in the eye that can lead to permanent blindness
  7. Intraocular pressure (IOP)
    Inner pressure of eye. Normal 12-22 mm Hg
  8. Iris
    Colored part of the eye that can expand or contact to allow the right amount of light to enter the eye
  9. Keratotomy
    Incision of the cornea to correct myopia
  10. Lacrimal Apparatus
    Structures that keep the surface of the eye moistened with lacriminal fluid (tears)
  11. Optic Disk
    Oscular end of the optic nerve where the retinal nerve fibers exit and the blood vessels enter
  12. Optic Nerve
    Bundle of nerve fibers located in the back of the eye that connects the retina to the brain
  13. Tonometry
    Use of a device to measure the pressure in the eye
  14. Trabecular Meshwork
    Small opening around the outer edge of the iris that form meshlike drainage canals surrounding the iris. Aka Schlemm's canal
  15. Glaucoma Facts
    • 1) open angle: most common
    • 2) second leading cause of blindness worldwide
    • 3) 1/6 afflicted develop bilateral blindness
  16. Beta-Blocker Common Ending
  17. Beta-Blockers Treats;
    Open Angle Glaucoma
  18. Beta-Blocker Types
    • betaxolol: Betoptic S
    • levobunolol: Betagan
    • timolol maleate: Timoptic

    • Combo: (most common)
    • timolol+lantanoprost: Xalcom
  19. When is B-blocker betaxnol preferred?
    For patients with asthma or heart failure
  20. Alpha-Blockers Job;
    Prevention & Treatment of IOP (Inner Eye Pressure)
  21. Alpha-Blocker Types;
    • apraclonidine: Iopidine
    • brimonidine: Alphagan
  22. Carbonic Anhydrase Inhibitors Common Ending;
  23. Carbonic Anhydrase Inhibitor Treats;
    Open Angle Glaucoma
  24. Carbonic Anhydrase Inhibitor Types;
    • brinzolamide: Azorpt
    • dorzolamide: Trusopt

    • Combo:
    • dorzolamide+timolol: Cosopt
  25. Drugs that Increase Aqueous Humor Drainage (4)
    • 1) Adrenergic agonists
    • 2) Cholinergic agonists
    • 3) Prostaglandin analongs
    • 4) Acetylcholinestetase inhibitors
  26. Adrenergic agonist; Dipivifren
    Prodrug that needs to be activiated with epinephrine
  27. Cholinergic Agonist Type;
    pilocarpine: Akarpine, Diocarpine, Isopto Carpine, Pilopine HS, Salagen
  28. Prostaglandin Analog Common Ending
  29. Prostaglandin Types;
    • bimatoprost: Lumigan
    • latanoprost: Xalatan
    • travoprost: Travatan
  30. Warning Labels for Glaucoma Drops
    • (for chronic not accute)
    • Don't Discontinue
    • Wash Hands
    • Avoid Tip Contamination
    • Discard Discolored Drops
    • Remove Contacts for 15 mins