Unit 39.txt

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Author:
Cloe
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155590
Filename:
Unit 39.txt
Updated:
2012-05-24 02:13:24
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Pharmacology Fungal Infections
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Chapter 39 of the Pharmacology for Pharmacy Technicians textbook by Moscou/Snipe
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  1. Antifungal
    Drugs used to treat fungal infections
  2. Candida
    • Type of fungus known as yeast
    • Affects skin folds & mucous membranes
  3. Dermatophytes
    Group of fungi responsible for most fungal skin, hair and nail infections
  4. Fungus
    Primitive plant that reproduces by budding, releasing spores or fusing hyphae
  5. Mycoses
    General term for fungal infections
  6. Onychomycoses
    • Fungal infection of the nails.
    • Aka tinea unguium
  7. Vulvovaginal Candidiasis
    Vaginal Yeast Infection or Moniliasis
  8. Types of Fungi
    Mold, Mildew, Yeast and Mushrooms
  9. tinea corporis
    Ringworm of the body
  10. times capitis
    Ringworm of the scalp
  11. tinea manus
    Hand infection
  12. Preventing Athlete's Foot
    • Keep clean and dry
    • Wear open shoes to breathe
    • Avoid bare feet in public area
    • Wear cotton socks
    • Change daily
    • Use antifungal powders for prevetion
  13. Drugs causing Yeast Infection
    • Antibiotics
    • Corticosteroids
    • The Pill
    • Immunosuppressives
    • Hormone Replacements
  14. How Anti-fungals Work
    • 1) Destroy fungus cell membrane
    • 2) Inhibit cell wall synthesis
    • 3) interfer w/ nucleic acid synthesis
  15. Common Ending for Imidazoles and Triazoles
    "-azoles"
  16. "-azoles" treat;
    • Athlete's Foot
    • Yeast Infections
    • Jock Itch
    • Ringworm
  17. "-azoles" work by;
    Inhibit fungal cell wall synthesis
  18. "-azoles" Formulations
    • Topicals; cream, gel, lotion, shampoo
    • Oral;
    • Suppositories;
  19. clotrimazole
    Canesten 1
  20. miconazole
    Monistat 1, 3 & 7
  21. ketoconazole
    Nizerol Shampoo
  22. Allyamine Antifungals
    • terbinafine; Lamisil
    • Prescription only
    • Treats; nail infections
  23. Polyene Antifungal
    • nystatin; Nystop
    • Treats; candida infections
    • Oral & Topical only
  24. Thiocarbamates
    • tolnaftate; Tinactin, Dr Scholls
    • Treats; Ringworm, Althlete's Foot & Jock Itch
  25. Echinocandin Antifungals
    • "-fungin"
    • Parental use only
    • Treats Candida & Aspergillus
  26. ciclopirox
    Treats Athlete's Foot, Ringworm & mild Onychomycosis
  27. grisefulvin
    Oral tabs for Onychomycosis


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