Unit 41.txt

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Author:
Cloe
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155593
Filename:
Unit 41.txt
Updated:
2012-05-24 02:19:36
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Pharmacology Acne
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Description:
Chapter 41 of the Pharmacology for Pharmacy Technicians textbook by Moscou/Snipe
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  1. Acne Vulgaris
    Most common form of acne
  2. Blackhead
    Open comedone
  3. Comedone
    Most characteristic sign of acne
  4. Cysts
    End product of pustules or nodules
  5. Keratolysis
    Softening and shredding of the horney outer layer of the skin
  6. Keratolytic Agent
    Skin peeling agent
  7. Milia
    Tiny little bumps of shed skin cells trapped in pockets on the skin.
  8. Nodule
    Ruptured pustules that form abscesses
  9. Papule
    Obstructed follicle that becomes inflamed
  10. Pilosebaceous units (PSUs)
    Consists of a sebaceous gland connected to a fine hair follicle
  11. Pustule (pimples)
    Larger lesions that are more inflamed than papules and can be superficial or deep
  12. Whitehead
    Closed comedone
  13. Factors that Worsen Acne
    • 1) changing hormone levels
    • 2) oil from skin products
    • 3) grease from work
    • 4) pressure from sport equipment & backpacks
    • 5) enviro irritants
    • 6) squeezing or picking
    • 7) aggressive scrubbing
    • 8) stress
  14. Drugs which Worsen Acne
    • 1) anabolic steroids
    • 2) bromides
    • 3) corticosteroids
    • 4) isoniazid
    • 5) lithium
    • 6) phenytoin
    • 7) azathioprine
    • 8) tetracycline
    • 9) quinidine
    • 10) B vitamins
  15. Treatment of Mild Acne
    • Topical OTCs;
    • 1) Keratolytics
    • 2) Antibactetials
    • 3) Benzoyl Perixide
    • Requires 4-8 weeks to see improvement
  16. Comedolytics (keratolytics)
    • 1) Salicylic Acid
    • 2) Sulfer-Resorcinol Combo
    • Treats; black/white heads
  17. Topical Antibacterials
    • 1) Sulfer and sulfacetamide combo
    • Treats; acne, rosacea and seborrheic dermatitis
  18. Benzoyl Peroxide
    • Most widely used OTC
    • Treats; noninflammatory acne
  19. Treatment of Moderate Acne
    • 1) physical exctraction
    • 2) UV light therapy
    • 3) oral antibiotics
    • 4) vitamin A (retinoids)
    • 5) Pr strength keratolytics
    • 6) oral contraceptives
  20. Oral Antibiotics for Acne
    • 1) tetracycline
    • 2) erythromycin
    • 3) doxycycline
    • 4) minocycline
  21. Topical Antibiotics for Acne
    • 1) clinamycin
    • 2) erythromyin
    • 3) metronidazole (cheapest)
    • 4) sulfacetamide
  22. Retinoids
    • 1) adapalene - Differin
    • 2) tretinoin - Retin-A
    • 3) tazarotene
    • 4) azelaic acid
  23. Treatment of Severe Acne
    • 1) surgical drainage
    • 2) corticoid injections
    • 3) isotretinoin
    • 4) oral antibiotics
    • 5) oral contraceptives
  24. Isotretinoin
    • Accutane;
    • Treats in 15-20 weeks
    • AVOID PREGNANCY
  25. Treatments for Hormonal Acne
    • 1) oral contraceptives
    • 2) corticosteroids
    • 3) anti-androgens

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