HMIT 210

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  1. What are the course Objectives
    • •Differentiate physiology and pathophysiology
    • •Examine etiology of disease and its implications
    • •Examine outcomes of different pathological conditions; effects on quality of life
    • •Evaluate potential pharmacological treatments
    • •Differentiate pharmacodynamics and pharmacokinetics
    • •Differentiate
    • side effect from adverse reaction
    • •Explain routes of administration
    • •Identify drug classifications and categories
    • •Differentiate between drug trade, generic, chemical names
    • •Understand drug safety regulations
    • •Demonstrate ability to use drug reference materials
  2. •What is pathophysiology?
    • •The study of physiological
    • processes leading to disease
  3. •What is pharmacology?
    • •The study of chemicals or drugs on living tissue
    • •Chemicals or drugs help to
    • diagnose, treat, cure, prevent disease or correct the pathophysiology of living
    • tissues
  4. How many lectures
  5. What are the require text
    • •Zelman M et al. (2010) Human Diseases A Systemic Approach, 7th
    • •Kamienski M and Keogh J (2006) Pharmacology
    • demystified, NY
  6. How many possible point
  7. •Homeostasis
    • (AKA steady state)
    • •A system in which a particular variable is not changing but energy must be continuously added to maintain this variable constant
    • •A state of equilibrium
  8. •Disease
    •A state of disequilibrium
  9. •Disease
    •A state of disequilibrium
  10. •Pathology
    •The medical science that examines the essential nature of disease, especially changes of structure and function in body tissues and organs that cause or are caused by disease
  11. •Pathophysiology
    •The study of physiological processes leading to disease
  12. Manifestation of Diesaes
    • Signs
    • Symptoms
    • Syndromes
    • Diagnosis
    • Physical exam
  13. examples of physical examination measurements
    • Blood Preasure
    • Temapature
    • Palpation
    • Heart (pulse)rate
    • Lung sounds
    • Reflex
  14. Examples of Dieanostic Test
    •For visualizing structural and functional changes

    • •Examples
    • •Computer tomography (CT) scans
    • •Magnetic resonance imaging (MRI)
    • •Ultrasound
    • •Nuclear medicine
    • •Biopsy
  15. terms that describe disease
    • Prognosis
    • Remission
    • Exacerbation
    • Relapse
    • Complication
    • Sequela
    • Mortality
    • Morbidity
    • Prevalence
    • Incidence
    • Eqpidemology
  16. •Prognosis
    • •Predicted course and outcome of the diseaseAcute
    • chronic Terminal
  17. Acute-
    •eg., influenza, measles, common cold
  18. Chronic-
    •diabetes, heart disease, cancer, osteoarthritis
  19. •Remission
    •Signs and symptoms of a disease subside
  20. •Exacerbation
    • •Reoccurrence
    • of symptoms
  21. •Relapse
    • •When
    • disease returns weeks or months after apparent cessation

    •Eg., leukemia, ulcerative colitis
  22. •Complication
    • •A
    • secondary disease as a result of a primary disease
  23. •Sequela
    •Pathological condition resulting from disease, injury, or trauma
  24. •Mortality
    • •A
    • measure of the number of deaths attributed to a disease
  25. •Morbidity
    •The rate of incidence of disease
  26. •Prevalance
    •The number of cases of a disease occurring at a given time in a specified population
  27. •Incidence
    •The number of new cases of a disease occurring at a given time in a specified population
  28. •Epidemiology
    •The study of the occurrence ,transmission, distribution, and control of disease
  29. •Pathogenesis
    •The source or cause of disease together with its development
  30. •Lesion
    • •Root cause of disease
    • •Damaged gene or enzyme, abnormal cells, tissues, or organs
  31. Causes of Disease
    • Inflamation/autoimmunity/allergey
    • Infectin
    • Neoplasm
    • Heredity
    • Malutrition
    • Stress
  32. What is the difference between known and unknown diseases
    • •Disease where cause is known
    • •Procedures that cure or reduce symptoms of disease
    • •Surgery
    • •Pharmacological agents
    • •Disease where cause is unknown
    • •Palliative or symptomatic
  33. Herbal Therapy Definition
    AKA Medicinal botany
    • •Usually involves ingesting plant or part of plant
    • •To determine if plant or its parts have palliative effect on symptoms of an ailment
    • •Usedto treat common ailments such as
    • •Acne
    • •Bladder infection
    • •Candida
    • •Diabetes
    • •Ear infection
  34. •Hazards of herbal therapy
    • •Lack of manufacturing standards and regulatory oversight
    • •Drug-herbal therapy interaction
    • •Route of administration
  35. Be able to differentiate between “bad” and
    “good” reputation of herbal therapy
    • •Herbs are not typically prescribed
    • •Few pharmacy schools offer courses in botanical remedies
    • •Pharmaceutical courses focus more on misuse of herbal therapies than proper use
    • •Herbal therapies cannot be patented
    • •Not regulated by FDA
    • •In USA, not covered by health insurance
  36. Be able to differentiate between “bad” and“good” reputation of herbal therapy
    • •In
    • 1992, US Congress instructed National Institute of Health to develop an office
    • of alternative medicine

    • •National
    • Center for Complementary and Alternative Medicine (NCCAM,

    • •To support research studies of
    • alternative therapies including herbals
Card Set:
HMIT 210
2012-05-27 19:26:00
Patho pharm

Week 1 Quiz
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