Aminophylline is a methylxanthine that prolongs bronchodilation and decreased mucus production and has mild cardiac and CNS stimulating effects.
Bronchospasm in asthma with COPD refractory to sympathomimetics and other bronchodilators and in CHF.
Uncontrolled cardiac dysrhythmias.
Cardiovascular disease, hypertension, or taking theophylline, hepatic impairment, diabetes, hyperthyroidism, young children, glaucoma, peptic ulcers, acute influenza or influenza vaccination, and the elderly. Watch for PVCs or tachycardia. May cause hypotension.
- - Dosage/Route: 250 to 500 mg IV over 20 to 30 mins.
- Pedi: 6 mg/kg over 20 to 30 mins. Max 12 mg/kg/day