PCP

Card Set Information

Author:
vidya
ID:
157352
Filename:
PCP
Updated:
2012-06-05 19:17:17
Tags:
Wnt PCP
Folders:

Description:
Non-canonical Wnt signalling
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  1. What is Non canonical Wnt pathway
    Regulates polarized re-organization of actin cytoskeleton for cell motility in a B-catenin independant manner
  2. Examples for Non-canonical Wnt signalling
    Gastrulation movements, dorsoventral patterning, neuronal migration, cochlear hair cell polarity, cardiogenesis and cancer progression
  3. Non-canonical Wntsignalling pathway chain?
    Two possibilities:

    1. Dvl Rac c-jun (N-terminal kinase)

    2. Dvl Rho Rho-associated kinase

    (Rac and Rho are Rho family of small GTPases)

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