HIV Drugs

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Author:
jheneale
ID:
15738
Filename:
HIV Drugs
Updated:
2010-04-22 18:06:26
Tags:
Nrs
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Description:
Antiretrovirals
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  1. HIV Drugs (9)
      1. Zidovudine
      2. Delavirdine
      3. Indidinavir
      4. Didanosine
      5. Efavirenz
      6. Saquinavir
      7. Lamivudine
      8. Tenofovir
      9. Enfuvirtide
  2. Zidovudine
    Mechanism side effects (11) DT (5)
    NRTI

    • Fatigue
    • GI intolerance
    • Nausea
    • Headache
    • Malaise
    • Insomnia
    • Nuetropenia (CBC)
    • Anemia (CBC)
    • Bone marrow suppression (CBC)
    • Granulocytopenia (CBC)
    • Hepatitis (Liver)
  3. Delavirdine
    Mechanism Side effects (3) DT (1) note (2)
    NNRTI

    • Nausea
    • Skin
    • Rash
    • Liver
    • function change (Liver)
    • Note:
    • Do NOT MIX TABLETS IN 3OZ+ WATER
  4. Indinavir
    Mechanism (1) Side effects (3) note (2)
    PI

    • Nausea
    • Diarrhea
    • Kidney stones
    • Note:
    • Hydrate (2-4 L/d)
    • DO NOT TAKE W/ GRAPEJUICE
  5. Didanosine
    Side effects (6) DT (4) Note (2)
    Mechanism
    • NRTI
    • GI intolerance
    • Bone marrow suppression (CBC)
    • Pancreatitis (serum amylase)
    • hepatitis (liver)
    • hyperuricemia (U/A)
    • painful peripheral neuropathy

    • Note:
    • used for pt's who cannot tolerate zidovudine.
    • MUST be chewed or dissolved to release buffer UNLESS Videx EC (time released)
  6. Efavirenz
    Side effects (6)
    Note (1)
    Mechanism
    • NNRTI
    • Rash
    • Dizziness
    • Trouble concentrating
    • Unusual dreams
    • Confusion
    • Encephalopathy (brain dysfunction)

    • Note:
    • take at bedtime to help w/ S.E
  7. Saquinavir
    S.E (3)
    Note (1)
    Mechanism
    • PI
    • nausea
    • headache
    • dirarrhea

    Note: Refrigerate capsules; ok at room temp for 90 DAYS
  8. Lamivudine
    S.E (2)
    Note (1)
    mechanism
    • NRTI
    • Nausea
    • Nasal Congestion

    • Note:
    • used to treat HIV and Hep B
  9. Combination Drugs
    mechanism
    • NRTI
    • Zidovudine and Lamivudine (Combivir)
    • Zidovudine Lamivudine Abacavir (Trizivir)
  10. Tenofovir
    S.E (2)
    mechanism
    • NRTI
    • nausea
    • vomitting
  11. Enfuvirtide
    S.E (4)
    Note (1)
    mechanism
    • FI/EI
    • nausea
    • skin irritation @ site
    • insomnia
    • peripheral nueropathy

    • Note:
    • INJECT SQ B.I.D ROTATE SITES

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