Exam 1: Embryology of CNS
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What happens to the neural plate (ectoderm) during the third week?
at rostral end of embryo (in front of primitive pit) the neural plate appears at 21 days
During the third week, what are the neural folds fromed from?
lateral edges of neural plate
During the third week, what is the neural tube formed from?
closure of neural folds
During the third week, what happens to the neuropores?
they close on the 25th and 27th days
What are neuropores?
- openings on each side of the neural tube
- the beginning of the CNS
What happens at 5 weeks?
primary brain vesicles
What are the three primary brain vesicles?
- 1. prosencephalon
- 2. mesencephalon
- 3. phombencephalon
What is the prosencephalon also known as?
What does the telencephalon from?
What are the divisions of the prosencephalon?
What is the diencephalon?
outgrowth of optic vesicles
What is the mesencephalon also known as?
What is the rhombencephalon also known as?
What is the metencephalon?
pons and cerebellum
What is the myelencephalon?
When do flexures occur?
at 28 days
What are the 3 flexures?
- 1. cephalic flexure
- 2. cervical flexure
- 3. pontine flexure
Where is the cephalic flexure?
located in midbrain region
Where is the cervical flexure?
at junction of hindbrain and spinal cord
Where is the pontine flexure?
at junction of metencephalon and myelencephalon
What is the central canal?
- lumen of spinal cord
- continuous with brain vesicles
Which brain vesicle contains the 4th ventricle?
Which brain vesicle contains the 3rd ventricle?
Where are the lateral ventricles found?
cerebral hemispheres (telencephalon)
What are the lateral ventricles filled with?
What are the lateral ventricles contected to?
the third ventricle
What connects the lateral ventricle to the third ventricle?
foramena of Monroe (interventricular foramena)
What connects the 3rd and 4th ventricles?
aqueduct of Sylvius (cerebral aqueduct)
What is the pathway of CSF?
L/R lateral and medial apetures (in wall of 4th ventricle) opens to subarachnoid space
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