Anti-Emetics

Card Set Information

Author:
wesparm
ID:
158471
Filename:
Anti-Emetics
Updated:
2012-06-12 21:45:09
Tags:
Medic 13
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Description:
Anti-Emetic medic drugs
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  1. Metoclopramide (Reglan)
    Anti-Emetic

    - Description: Metoclopramide is a Dopamine antagonist similar to procainamide, but with few anti-dysrhythmic or anesthetic properties. Its anti-emetic properties stem from gastric emptying and desensitization of the vomiting reflex.

    - Indications: Nausea and vomiting

    - Contraindications: Hypersensitivity, seizure disorders, GI obstruction or perforation, and breast cancer.

    - Precautions: CHF, hypokalemia, renal impairment, GI hemorrhage, intermittant porphyria.

    • - Dosage/Route: 10 - 20 mg IM; 10 mg slow IV (over 2-4 minutes)
    • Pedi: 1-2 mg/kg/dose
  2. Promethazine (Phenergan)
    Anti-Emetic

    - Description: Promethazine is an anticholinergic agent that enhances the effects of analgesics and potent anti-emetic.

    - Indications: Nausea and Vomitting, motion sickness, enhance effects of analgesics, and to induce sedation.

    - Contraindications: None

    - Precautions: Hepatic, respiratory, or cardiac impairment, asthma, hypertension, elderly, debilitated patients.

    • - Dosage/Route: 12.5-25 mg IV/IM/PR
    • Pedi: 0.5 mg/kg IV/IM/PR
  3. PROCHLORPERAZINE (Compazine)
    Antiemetic

    - Description: Prochlorperazine is a phenothiazine derivative similar to chlorpromazine with potent antiemetic properties and fewer sedative, hypotensive, and anticholinergic effects.

    - Indications: Severe nausea and vomiting or acute psychosis.

    • - Contraindications: Hypersensitivity to
    • phenothiazines coma or depression.

    - Precautions: Breast cancer, children with acute illness or dehydration.

    • - Dosage/Route: 5 to 10 mg IV/IM.
    • Ped: 0.13 mg/kg IV/IM/PR if > 10 kg or > 2 years.
  4. Zofran
    Anti-Emetic

    - Description: selective blocking agent of seratonin 5-HT3 receptor type

    - Indications: Prevention of nausea and intractible vomiting.

    - Contraindications: None

    - Precautions: may mask a progressive ileus and/or gastric distension.

    - Dosage/Route: 4 mg IV or PO

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