Card Set Information
Class I anti-arrhythmics block which channels?
Class II anti-arrhythmics block which channels?
Calcium channels (indirect effect)
Class III anti-arrhythmics block which channels?
Class IV anti-arrhythmics block which channels?
Although Amiodarone is considered a class III anti-arrhythmic, what other channels does it block?
Sodium and Calcium channels
List Class Ia anti-arrhythmics:
- Quinidine gluconate/sulfate/polygalacturonate
List Class Ib anti-arrhythmics:
List Class Ic anti-arrhythmics:
List class II anti-arrhythmics:
List class III anti-arrhythmics:
List class IV anti-arrhythmics:
Quinidine GLUOCONATE (5)
Quinaglute, Dura-Tabs, Duraquin, Quinalan, Quinatime
(not recommended IV)
Quinidine SULFATE (4)
Quinidex, Extentabs, Cin-Quin, Quinora
Cordarone, Pacerone, Nexterone
If AF is present for > 48 hours or unknown duration, anticoagulat with warfarin for _____ weeks prior to cardioversion, and continue for at least _____ weeks
sinus rhythm has been restored.
Prior to cardioversion, patients must receive _____ or ______. Once sinus rhythm restored, patients should receive warfarin for at least _______ weeks.
Unfractionated heparin; Low molecular weight heparin; 4
What does CHADS2 score represent?
It determines the risk of stroke in patients with AF
C = CHF = 1 point
H = HTN = 1 point
A = Age over 75 = 1 point
D = Diabetes = 1 point
Stroke or TIA = 2 points
What are the treatments recommended for a score of 0, 1, and >/equal to 2.
0 = ASA 81-325 mg/day
1 = 81 - 325 mg/day OR warfarin INR 2-3
>2 = warfarin INR 2-3
If patient do not want to take warfarin or if risks outweigh benefits, addition of ___________ can be added to ASA therapy.
Which two genes account for variablity in warfarin therapy if mutated?
CYP2C9 & VKORC1