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List all the resistances that involved with Aminoglycosides.
1) Reduced access
- Efflux pump via pseudomonas or acinetobactor
- Reduced permeability via porin selection or mutation
2) Target alteration
- Streptomycin via a 30S subunit mutation
What are the types of epithelial ovarian tumors?
SEROUS = cystadenoma & cystadenocarcinoma
Mucinous = cystadenoma & cystadenocarcinoma
clear cell carcinoma
What are the 4 endometrial neoplasias?
Endometrioid - estrogen exposure
Non-endometrioid - estrogen deficiency
Leiomyoma- estrogen only promotes. Bundles and whorls
Leiomyosarcoma - Lung metastasis
What are the 4 causes of thrombocytopenia?
1. Decreased production in the BM
2. Inc megakaryocytes in BM -> decreased survival
What is the disease and the characteristics that is caused by ADAMTS13 deficiency?
Thrombotic thrombocytopenic purpura
3. Microangiopathic hemolytic anemia
4. Kidney failure
5. Mental status change
What is Glanzmann thrombasthenia?
Defect in glycoprotein IIb-IIIa -> no integrin that binds fibrinogen -> no aggregation.
Pathophysiology of rubeosis iridis
VEGF --> new blood vessels in the iris and can block the anterior chamber angle -> increased intraocular pressure.
What shifts the oxygen saturation curve to the right?
Decreased O2 affinity
increased metabolic needs
What are the symptoms present with a stroke patient?
Sensory kept but cannot describe the object, no 2 point discrimination, graphesthesia, no sharp or dull discrimination.
When would the be loss of sensation in the I/L face but C/L extremities?
If there is a lesion in the thalamus.
What is the equation for prevalence using incidence?
Equation for odds