Cancer part 1

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Cancer part 1
2012-06-22 12:03:55
HMIT 210 cancer chapter

question 1-5
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  1. Hyperplaisia 
    Noncanerous growth consisting of rapidly dividing cells leading to an increased number of  normal cells
  2. Mild Displasia
    • Noncanerous abnormal cell growth characterized by the loss of normal tissue arrangement and cell structure
    • Cells may have changes in DNA and/or
    • Cells may have structral changes in the nuycleus 
  3. Carcinoma in situ
    • in situ (latin for in location or place)
    • Unctolled cell grwoth that remains in locatio or place
    • (does not invade surrounding tissue)
  4. Cancer
    Unctrolled cell growth and invasion into surrounding tissue
  5. Feature of Cancer
    • Not a single disease
    • Over 100 types and subtypes of human cancer
    • Indiscriminant
    • Leading casue of death worldwide
    • affects 2 of every 3 families 
  6. Main types of cancer and overall mortality
    • Lung- 1.3 million deaths yearly
    • Stomach- ~1 million deaths yearly
    • Liver- ~662K deaths yearly
    • Colon- ~665K deaths yearly
    • Breast- ~502K deaths yearly
  7. Tumor
    • Swelling
    • Describes the severity of a person's cancer based on the extent of the orginal (primary) tumor and whether or not cancer has spread in the body
  8. Why is tumor staging important
    • Helps doctor plan the appropriate treatment
    • Can be used to estimate a patient’s prognosis
    • Important in identifying clinical trials that may be suitable for a particular patient
    • Helps health care providers and researchers exchange information about patients
    • Provides common terminology for evaluating and comparing the results of similar/dissimilar clinical trials
  9. •TMN staging system based on
    • •Tumor (T) -Extent of the tumor
    • •Nodes (N) -Whether cancer cells have spread to nearby (regional) lymph nodes
    • •Metastasis (M) - Whether distant (to other parts of body) metastasis has occurred
  10. Neoplasia
    New Growth
  11. What is the tissue of origin (epithelial cells or connective tissues)
    • •Tumor (T) -Extent of the tumor
    • •Nodes (N) -Whether cancer cells have spread to nearby (regional) lymph nodes
    • •Metastasis (M) - Whether distant (to other parts 
    • of body) metastasis has occurred
  12. 2 types of tissue of orgin
    epithelial cells or connective tissues
  13. Benign tumors are considered 
    noncancerous, localized to a tissue, and end in oma
  14. Malignant tumors consist of 
    rapidly dividing cells, invade normal tissue, metastasize to distant sites, and end in carcinoma or sarcoma
  15. Epithelial Cells and Benign
    • Adenoma
    • Papilloma
    • Squamous cell papilloma
    • Liver Cell Adeonoma
    • Renal Tubular ademoa
  16. Connective Tissue and  Benign
    • Fibroma
    • Lipoma
    • Chandroma
    • Osteoma
    • Hemangioma
    • Rhabdomyoma
    • Leimyoma
  17. Epithelial Cells and Malignant
    • Adenoscarcoma
    • Paillary andenocarcioma
    • Squamaous Cell carcinoma
    • Hepatocellura Carcinoma
    • Renal Cell Carcinoma
  18. Connective Tissue and Malignant
    • Fibrosarcoma
    • Liposarcoma
    • Chondrosarcoma
    • Osterscarcoma
    • Angiosarcoma
    • Rhabdomayosarcoma
    • Leiomyosarcoma
  19. four factors that regulate normal cell growth and repair damaged tissue
    • Growth factors
    • Growth inhibitors
    • Cyclins - Cell Cycle Proteins
    • Apoptosis - Programmed cell death, a normal componet of the development and health of mulitcellular organisms