Drug Doses for VTE, ACS, and HF

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Author:
mcucullu
ID:
159924
Filename:
Drug Doses for VTE, ACS, and HF
Updated:
2012-06-24 18:30:03
Tags:
drug doses venousthromboembolism VTE acute coronary syndrome ACS heart failure HF
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Description:
These are the doses we are expected to know for VTE, ACS, and HF.
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  1. Heparin Loading Dose
    (VTE)
    (Weight-based) 
    • 80-100 units/kg
    • Max: 10,000 units 
  2. Heparin infusion rate dose
    (VTE)
    (Weight-based) 
    • 17-20 units/kg/hr
    • Max: 2,300 units/hr 
  3. Heparin loading dose
    (VTE)
    (Standard) 
    5,000 units
  4. Heparin infusion rate dose
    (VTE)
    (Standard)
    1,000-1,200 units/hr
  5. Enoxaparin treatment dose
    (Regular renal function)
    1 mg/kg q 12 hr
  6. Enoxaparin treatment dose
    (CrCl < 30 mL/min)
    1 mg/kg q 24 hr
  7. Enoxaparin prophylactic dose
    (Regular renal function)
    40 mg q 24 hrs SQ
  8. Enoxaparin prophylactic dose
    (CrCl < 30 mL/min) 
    30 mg q 24 hrs SQ
  9. Protamine sulfate dose
    (1st dose)
    (LMWHs) 
    1 mg of protamine sulfate for 1 mg of LMWH administered within 8 hrs
  10. Protamine sulfate dose
    (2nd dose)
    (LMWHs) 
    0.5 mg of protamine sulfate for 1 mg of LMWH administered within 8 hrs
  11. Protamine sulfate dose
    (UFH) 
    • 1 mg of protamine sulfate for every 100 units of UFH
    • Max: 50 mg of protamine sulfate 
  12. Carvedilol doses
    (ACS)
    3.125-6.25 mg BID
  13. Carvedilol target dose
    (ACS)
    25-50 mg BID
  14. Carvedilol Phosphate doses
    (ACS)
    10-20 mg QD
  15. Carvedilol Phosphate target dose
    (ACS) 
    80 mg QD
  16. Metoprolol Tartrate doses
    (ACS)
    100 mg BID or 25-50 mg q 6 hrs
  17. Metoprolol Tartrate target dose
    (ACS)
    25-100 mg BID
  18. Metoprolol Succinate doses
    (ACS) 
    12.5-100 mg QD
  19. Metoprolol Succinate target dose
    (ACS) 
    200 mg QD
  20. Atenolol dose
    (ACS)
    50 mg BID
  21. Atenolol target dose
    (ACS)
    100-200 mg QD
  22. Captopril doses
    (ACS) 
    6.25-12.5 mg TID
  23. Captopril target dose
    (ACS) 
    50 mg TID
  24. Enalapril doses
    (ACS) 
    2.5-5 mg QD
  25. Enalapril target dose
    (ACS)
    20 mg QD
  26. Fosinopril doses
    (ACS)
    5-10 mg QD
  27. Fosinopril target dose
    (ACS) 
    40 mg QD
  28. Lisinopril doses
    (ACS) 
    5 mg QD
  29. Lisinopril target dose
    (ACS)
     
    10 mg QD
  30. Ramipril doses
    (ACS) 
    2.5 mg BID
  31. Ramipril target dose
    (ACS) 
    5 mg BID
  32. Candesartan dose
    (ACS) 
    4 mg QD
  33. Candesartan target dose
    (ACS) 
    32 mg QD
  34. Valsartan dose
    (ACS) 
    20 mg BID
  35. Valsartan target dose
    (ACS) 
    160 mg BID
  36. Captopril doses
    (HF) 
    6.25 mg TID
  37. Captopril target dose 
    (HF) 
    50 mg TID
  38. Enalapril doses
    (HF) 
    2.5 mg BID
  39. Enalapril target doses
    (HF) 
    10-20 mg BID
  40. Fosinopril doses
    (HF) 
    50-10 mg QD
  41. Fosinopril target dose
    (HF) 
    40 mg QD
  42. Lisinopril doses
    (HF) 
    2.5-5 mg QD
  43. Lisinopril target doses
    (HF) 
    20-40 mg QD
  44. Ramipril doses
    (HF) 
    1.25-2.5 mg QD
  45. Ramipril target dose
    (HF) 
    10 mg QD
  46. Perindopril dose 
    2 mg QD
  47. Perindopril target doses
     
    8-16 mg QD
  48. Quinapril dose
    5 mg BID
  49. Quinapril target dose
    20 mg BID
  50. Trandolapril dose
    1 mg QD
  51. Trandolapril target dose
    4 mg QD
  52. Carvedilol dose
    (HF) 
    3.125 mg  BID
  53. Carvedilol target doses
    (HF) 
    25-50 mg  BID
  54. Carvedilol CR dose
    (HF) 
    10 mg QD
  55. Carvedilol CR target dose
    (HF) 
    80 mg QD
  56. Metoprolol XL dose
    (HF)
     
    12.5 mg QD
  57. Metoprolol XL target dose
    (HF) 
    200 mg QD
  58. Bisoprolol dose
    1.25 mg QD
  59. Bisoprolol target dose
    10 mg QD
  60. Candesartan doses
    (HF) 
    4-8 mg QD
  61. Candesartan target dose
    (HF) 
    32 mg QD
  62. Valsartan dose
    (HF) 
    40 mg BID
  63. Valsartan target dose
    (HF) 
    160 mg BID
  64. Losartan doses
    25-50 mg QD
  65. Losartan target doses
    50-100 mg QD
  66. Spironolactone dose
    12.5 mg QD
  67. Spironolactone target dose
    25 mg QD
  68. Eplerenone dose
    25 mg QD
  69. Eplerenone target dose
    50 mg QD
  70. Hydralazine dose
    25 mg TID
  71. Hydralazine target dose
    75 mg TID-QID
  72. Isosorbide Dinitrate dose
    10 mg TID
  73. Isosorbide Dinitrate target dose
    40 mg TID
  74. BiDil dose
    • 1 tab TID
    • (37.5 mg/20 mg) 
  75. BiDil target dose
    • 2 tabs TID
    • (75 mg/40 mg) 

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