- - Description: Heparin is a rapid-onset anticoagulant, enhancing the effects of
- antithrombin III and blocking the conversion of prothrombin to thrombin and fibrinogen to fibrin.
: To prevent thrombus formation in acute MI.
: Hypersensitivity; active bleeding or bleeding tendencies; recent eye, brain, or spinal surgery; shock.
: Alcoholism, elderly, allergies, indwelling catheters, elderly, menstruation, pregnancy, or cerebral embolism.
: 5,000 units IV, then 20,000 to 40,000 units over 24 hours.